84328-14-3Relevant academic research and scientific papers
Influence of co-solvents in the highly efficient selective monohydrolysis of a symmetric diester
Niwayama, Satomi,Wang, Hezhen,Hiraga, Yoshikazu,Clayton, J. Cole
, p. 8508 - 8510 (2007)
The influence of the co-solvents in the selective monohydrolysis of a symmetric diester, in an aqueous NaOH medium at 0 °C, has been examined. The reactions were found to proceed through reaction media consisting of water with a small amount of a co-solvent and the starting symmetric diester. Slightly polar aprotic solvents that are slightly miscible with water, such as THF and acetonitrile, were found to be effective co-solvents.
Synthetic studies of new CMP-sialic acid analogues applying a novel buffer-mediated rearrangement
Niwayama, Satomi,Kandula, Venkata Subbarao,Wang, Hezhen,Chen, Xiao
, p. 8757 - 8760 (2007)
Synthetic studies of analogues of cytidine monophosphate (CMP)-sialic acid as transition state mimics for sialylation are reported, applying selective monohydrolysis of a symmetric diester and a subsequent buffer-mediated regio- and stereospecific rearrangement we reported earlier.
SYNTHESIS OF HALF ESTERS
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Page/Page column 13, (2009/01/24)
A method for hydrolyzing an ester is provided. In accordance with the method, a compound A is provided which has first and second ester moieties. The compound is reacted in a liquid medium with a base having the formula MaXb,such that the first ester moiety is converted to a carboxyl moiety and the second ester moiety remains, wherein the ratio [Xk-]:[A] in the liquid medium is no greater than 1.6, and wherein k > 0.
Effects of counter cations in selective monohydrolyses of symmetric diesters
Niwayama, Satomi,Rimkus, Audrius
, p. 498 - 500 (2007/10/03)
Monohydrolyses of symmetric diesters were carried out using several aqueous inorganic bases, LiOH, NaOH, KOH, and CsOH. The more reactive bases showed higher selectivities in the monohydrolyses of acyclic symmetric diesters.
Catalytic Isomerisation of Water-Soluble Quadricyclane to Norbornadiene Derivatives Induced by Cobalt-Porphyrin Complexes
Maruyama, Kazuhiro,Tamiaki, Hitoshi
, p. 602 - 606 (2007/10/02)
In an aqueous alkaline solution, the exothermic isomerisation of quadricyclane derivatives to norbornadiene derivatives catalyzed by cobalt-porphyrin complexes was investigated.By catalytic action of cobalt 5,10,15,20-tetrakis(p-carboxyphenyl)porphyrin (Co-TPPC), thermally stable and water-soluble quadricyclane derivatives 1a-l isomerised to the corresponding norbornadiene derivatives 2a-l quantitatively and suddenly even at room temperature in an aqueous sodium carbonate solution.It was seen that larger hydrophobicities of 1 enhanced the isomerization rate.The attacking direction of cobalt porphyrins toward quadricyclanes might be to the five-membered ring, which was different from that suggested in the action of Rh catalyst, i.e., attack to the three-membered ring.
