84330-84-7Relevant academic research and scientific papers
PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS
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Page/Page column 211; 212, (2013/07/05)
The present invention provides compounds of the general formula (I), their salts and N- oxides, and solvates and prodrugs thereof (wherein the characters are as defined in the description). The compounds of the general formula (I) are inhibitors of Factor XIa, so that they are useful in the prevention of and/or therapy for thromboembolic diseases.
6-BENZOXAZINYL- AND 6-BENZOTHIAZINYL 2,3,4,5-TETRAHYDROPYRIDAZIN-3-ONES
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, (2008/06/13)
The synthesis of benzoxazinyl- and benzothiazinylpyridazinone compounds is described. The novel compounds are cardiotonic agents and inhibitors of phosphodiesterase. In addition, the compounds are useful as smooth muscle relaxants and bronchodilators
ARALKYLAMINOETHANOL HETEROCYCLIC COMPOUNDS
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, (2008/06/13)
Heterocyclic aminoethanols of the formula: Het--CHOH--CH 2--NH-aralkylwhere Het is a 6-10 membered N-heterocycle are disclosed. The compounds are useful as pharmaceuticals.
6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
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, (2008/06/13)
The synthesis of benzoxazinyl-pyridazinone compounds is described. The novel compounds are cardiotonic agents and inhibitors of phosphodiesterase fraction III. In addition, the compounds are useful as smooth muscle relaxants and bronchodilators
6-BENZOXAZINYL- AND 6-BENZOTHIAZINYL-2,3,4,5-TETRAHYDROPYRIDAZIN-3-ONES AND PHARMACEUTICAL USE
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, (2008/06/13)
The synthesis of benzoxazinyl- and benzothiazinyl-pyridazinone compounds is described. The novel compounds are cardiotonic agents and inhibitors of phosphodiesterase. In addition, the compounds are useful as smooth muscle relaxants and bronchodilators.
