84341-94-6

Basic information

• Product Name: Propanoic acid, 2-methyl-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (R)-
• CAS NO: 84341-94-6
• Molecular Formula: C12H16O5S
• Molecular Weight: 272.322
• Mol File: 84341-94-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-methyl-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methyl-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (R)-(84341-94-6)
• EPA Substance Registry System: Propanoic acid, 2-methyl-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (R)-(84341-94-6)

Safety Data

• Hazardous Substances Data: 84341-94-6(Hazardous Substances Data)

Upstream product

• 72657-23-9 methyl (R)-3-hydroxy-2-methylpropionate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 86961-08-2 methyl (S)-(-)-3-acetyl-thio-2-methylpropanoate 
• 60148-95-0 (R)-2,6-dimethylheptanoic acid methyl ester 
• 148290-12-4 (R)-2-Methyl-3-(p-toluenesulfonate)-propanal diethyl acetal 
• 1442105-08-9 C₁₂H₁₅IO₃S 
• 121749-23-3 Toluene-4-sulfonic acid (S)-3-hydroxy-2-methyl-propyl ester 
• 182486-32-4 (R)-methyl 3-{[(tert-butoxy)carbonyl]amino}-2-methylpropionate 
• 84506-41-2 methyl (2R)-3-azido-2-methylpropanoate 

Relevant articles and documents

Asymmetric syntheses of potent antitumor macrolides cryptophycin B and arenastatin A

Efficient and highly stereoselective syntheses of cryptophycin B and arenastatin A, potent cytotoxic agents, are described. An ester-derived titanium enolate mediated syn-aldol reaction was employed to generate the stereocenters C-5 and C-6. The route is convergent and provides a convenient access to the synthesis of structural variants of cryptophycins as well as members of its family. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).

SUBSTITUTED POLYCYCLIC ANTIBACTERIAL COMPOUNDS

The present description relates to substituted polycyclic compounds and forms and pharmaceutical compositions thereof and methods of using such compounds, forms or compositions thereof for treating or ameliorating Neisseria gonorrhoeae and Neisseria meningiditis.

A convergent synthesis of (+)-cryptophycin B, a potent antitumor macrolide from Nostoc sp. cyanobacteria.

[structure--see text] An efficient and highly stereoselective synthesis of cryptophycin B (2), a potent cytotoxic agent, is described. The ester-derived titanium-enolate-mediated syn-aldol reaction was employed to generate the stereocenters C(5) and C(6). The route is convergent and provides a convenient access to the synthesis of structural variants of cryptophycin B as well as members of its family.