84506-41-2Relevant academic research and scientific papers
Oligomers of N-Substituted β2-Homoalanines: Peptoids with Backbone Chirality
Lee, Kang Ju,Lee, Woo Sirl,Yun, Hyosuk,Hyun, Yu-Jung,Seo, Chang Deok,Lee, Chul Won,Lim, Hyun-Suk
supporting information, p. 3678 - 3681 (2016/08/16)
A new class of peptoid-based peptidomimetics composed of oligomers of N-substituted β2-homoalanines is reported. Design, solid-phase synthesis, and preliminary circular dichroism studies of oligomers of N-alkylated β2-homoalanines co
DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT
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Page/Page column 127, (2010/11/24)
The present invention relates to novel compounds exhibiting good inhibitory activity versus Dipeptidyl Peptidase-IV(DPP-IV), methods of preparing the same and pharmaceutical compositions containing the same as an active agent.
A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions
Shaw, Simon J.,Sundermann, Kurt F.,Burlingame, Mark A.,Zhang, Dan,Petryka, Joseph,Myles, David C.
, p. 1961 - 1964 (2007/10/03)
A collection of seven new 23,24-dihydrodiscodermolide analogues have been synthesized with modifications to the lactone ring, some of which show antiproliferative activities similar to discodermolide.
Total synthesis of cryptophycin 3
Danner, Paulami,Bauer, Matthias,Phukan, Prodeep,Maier, Martin E.
, p. 317 - 325 (2007/10/03)
The depsipeptide cryptophycin 3 (5) and the cryptophycin analogue 43 were prepared from the corresponding four subunits, The tripeptide analogue 34 was acquired from the starting amino ester 33, which contains fragments D and C. After extension at the car
Asymmetric syntheses of potent antitumor macrolides cryptophycin B and arenastatin A
Ghosh, Arun K.,Bischoff
, p. 2131 - 2141 (2007/10/03)
Efficient and highly stereoselective syntheses of cryptophycin B and arenastatin A, potent cytotoxic agents, are described. An ester-derived titanium enolate mediated syn-aldol reaction was employed to generate the stereocenters C-5 and C-6. The route is convergent and provides a convenient access to the synthesis of structural variants of cryptophycins as well as members of its family. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).
A convergent synthesis of (+)-cryptophycin B, a potent antitumor macrolide from Nostoc sp. cyanobacteria.
Ghosh,Bischoff
, p. 1573 - 1575 (2007/10/03)
[structure--see text] An efficient and highly stereoselective synthesis of cryptophycin B (2), a potent cytotoxic agent, is described. The ester-derived titanium-enolate-mediated syn-aldol reaction was employed to generate the stereocenters C(5) and C(6). The route is convergent and provides a convenient access to the synthesis of structural variants of cryptophycin B as well as members of its family.
