84348-21-0

Upstream product

• 106-39-8 bromochlorobenzene 
• 95-82-9 2,5 dichloroaniline 
• 17333-85-6 4-chlorophenyldiazonium salt 
• 98-67-9 p-hydoroxybenzenesulfonic acid 
• 106-37-6 1.4-dibromobenzene 
• 1435-50-3 2-bromo-1,4-dichlorobenzene 
• 124-41-4 sodium methylate 
• 98-66-8 4-chloro-benzenesulfonic acid 
• 29682-41-5 2,5-dichloroiodobenzene 
• 1623-92-3 4-phenoxyphenylsulfonyl chloride 
• 108-24-7 acetic anhydride 
• 106-47-8 4-chloro-aniline 
• 106-48-9 4-chloro-phenol 
• 60-29-7 diethyl ether 

Downstream Products

• 825-93-4 4-chlorophenyl-methyl-dichlorosilane 
• 830-45-5 Si,Si,Si',Si'-tetrachloro-Si,Si'-dimethyl-Si,Si'-p-phenylene-bis-silane 
• 953-21-9 N-phenylcinnamaldimine 
• 15719-64-9 methylammonium carbonate 
• 106263-50-7 4-(2-chlorophenyl)-4-oxobutanoic acid 
• 35599-92-9 2,5-dichloro-mandelic acid 
• 107915-92-4 6-(2,5-dichloro-phenyl)-2-methyl-benzothiazole 
• 100526-88-3 3,6-dichloro-2-(2,5-dichloro-benzoyl)-benzoic acid 
• 4132-70-1 1,4-dichloro-2-isopropylbenzene 
• 1571-86-4 1,4-dibutyl-benzene 
• 650-67-9 1,4-dichloro-2-(1,1,2,2-tetrafluoro-ethyl)-benzene 
• 2944-32-3 1,4-bis-(4-chloro-anilino)-anthraquinone 
• 33226-99-2 1-(4-chloro-anilino)-4-methylamino-anthraquinone 
• 834-68-4 dichloro(4-chlorophenyl)(phenyl)silane 

Relevant academic research and scientific papers

Facile Synthesis of a Fully Fused, Three-Dimensional ?-Conjugated Archimedean Cage with Magnetically Shielded Cavity

The synthesis of molecular cages consisting of fully fused, ?-conjugated rings is rare due to synthetic challenges including preorganization, large strain, and poor solubility. Herein, we report such an example in which a tris-2-aminobenzophenone precursor undergoes acid-mediated self-condensation to form a truncated tetrahedron, one of the 13 Archimedean solids. Formation of eight-membered [1,5]diazocine rings provides preorganization and releases the strain while still maintains weak ?-conjugation of the backbone. Thorough characterizations were performed by X-ray, NMR, and UV-vis analysis, assisted by theoretical calculations. The cage exhibits a rigid backbone structure with a well-defined cavity that confines a magnetically shielded environment. The solvent molecule, o-dichlorobenzene, is precisely encapsulated in the cavity at a 1:1 ratio with multiple ?···?, C-H···?, and halogen···πinteractions with the cage skeleton, implying its template effect for the cage closing reaction. Our synthetic strategy opens the opportunity to access more complex, fully fused, three-dimensional ?-conjugated cages.

The graphite-catalyzed: ipso -functionalization of arylboronic acids in an aqueous medium: metal-free access to phenols, anilines, nitroarenes, and haloarenes

An efficient, metal-free, and sustainable strategy has been described for the ipso-functionalization of phenylboronic acids using air as an oxidant in an aqueous medium. A range of carbon materials has been tested as carbocatalysts. To our surprise, graphite was found to be the best catalyst in terms of the turnover frequency. A broad range of valuable substituted aromatic compounds, i.e., phenols, anilines, nitroarenes, and haloarenes, has been prepared via the functionalization of the C-B bond into C-N, C-O, and many other C-X bonds. The vital role of the aromatic π-conjugation system of graphite in this protocol has been established and was observed via numerous analytic techniques. The heterogeneous nature of graphite facilitates the high recyclability of the carbocatalyst. This effective and easy system provides a multipurpose approach for the production of valuable substituted aromatic compounds without using any metals, ligands, bases, or harsh oxidants.

Amplification of Trichloroisocyanuric Acid (TCCA) Reactivity for Chlorination of Arenes and Heteroarenes via Catalytic Organic Dye Activation

Heteroarenes and arenes that contain electron-withdrawing groups are chlorinated in good to excellent yields (scalable to gram scale) using trichloroisocyanuric acid (TCCA) and catalytic Brilliant Green (BG). Visible-light activation of BG serves to amplify the electrophilic nature of TCCA, providing a mild alternative approach to acid-promoted chlorination of deactivated (hetero)aromatic substrates. The utility of the TCCA/BG system is demonstrated through comparison to other chlorinating reagents and by the chlorination of pharmaceuticals including caffeine, lidocaine, and phenazone.

Selective Hydrogenations and Dechlorinations in Water Mediated by Anionic Surfactant-Stabilized Pd Nanoparticles

We report a facile, inexpensive, and green method for the preparation of Pd nanoparticles in aqueous medium stabilized by anionic sulfonated surfactants sodium 1-dodecanesulfonate 1a, sodium dodecylbenzenesulfonate 1b, dioctyl sulfosuccinate sodium salt 1c, and poly(ethylene glycol) 4-nonylphenyl-3-sulfopropyl ether potassium salt 1d simply obtained by stirring aqueous solutions of Pd(OAc)2 with the commercial anionic surfactants further treated under hydrogen atmosphere for variable amounts of time. The aqueous Pd nanoparticle solutions were tested in the selective hydrogenation reactions of aryl-alcohols, -aldehydes, and -ketones, leading to complete conversion to the deoxygenated products even in the absence of strong Br?nsted acids in the reduction of aromatic aldehydes and ketones, in the controlled semihydrogenation of alkynes leading to alkenes, and in the efficient hydrodechlorination of aromatic substrates. In all cases, the micellar media were crucial for stabilizing the metal nanoparticles, dissolving substrates, steering product selectivity, and enabling recycling. What is interesting is also that a benchmark catalyst like Pd/C can often be surpassed in activity and/or selectivity in the reactions tested by simply switching to the appropriate commercially available surfactant, thereby providing an easy to use, flexible, and practical catalytic system capable of efficiently addressing a variety of synthetically significant hydrogenation reactions.

Direct Transformation of Arylamines to Aryl Halides via Sodium Nitrite and N-Halosuccinimide

A one-pot universal approach for transforming arylamines to aryl halides via reaction with sodium nitrite (NaNO2) and N-halosuccinimide (NXS) in DMF at room temperature under metal- and acid-free condition is described. This new protocol that is complementary to the Sandmeyer reaction, is suggested to involve the in situ generation of nitryl halide induce nitrosylation of aryl amine to form the diazo intermediate which is halogenated to furnish the aryl halide.

Dimethyl sulfoxide-accelerated reductive deamination of aromatic amines with t-BuONO in tetrahydrofuran

An efficient method for the conversion of aryl amines into arenes by a one-pot reductive deamination has been achieved. It was found the reductive deamination using t-BuONO in tetrahydrofuran could be accelerated by dimethyl sulfoxide and provided the deamination products with good yields under mild conditions. A plausible mechanism is discussed.

A method for preparing a chlorobenzene (by machine translation)

The invention benzene, chlorine is the raw material synthetic a chlorobenzene, metal sulfide as catalyst improves the reaction yield, the reaction temperature is 20 - 60 °C, benzene catalyst levels of 0.5% (Wt), reaction time 40 - 65min, the chlorobenzene the yield of 80%, benzene conversion reaches 90% or more. (by machine translation)

Method for preparing mixed dichlorobenzene through batch method

The invention relates to a method for preparing mixed dichlorobenzene through a batch method. According to the present invention, benzene and chlorine gas are adopted as raw materials to synthesize dichlorobenzene, a metal sulfide is adopted as a catalyst to improve the reaction yield, the reaction temperature is 30-60 DEG C, the catalyst use amount is 0.5% (Wt) of benzene, the reaction time is 60-120 min, the dichlorobenzene yield achieves 93%, the m-dichlorobenzene yield is less than 1%, and the polychlorobenzene yield is less than 1%.

Generation of VBr? VBi? VO?? defect clusters for 1O2 production for molecular oxygen activation in photocatalysis

Defect engineering on a semiconductor surface can provide coordinatively unsaturated sites for molecular oxygen activation in photocatalysis. In this work, we demonstrated that the vacancy type was key to modulate the molecular oxygen activation process on BiOBr nanosheets. By regulating the reaction time, an oxygen vacancy (VO??), a double atom defect cluster (VBi? VO??) and triple atom clusters (VBi? VO?? VBi? and VBr? VBi? VO??) were accordingly generated on the surface, subsurface and bulk of BiOBr. More importantly, the newly-discovered VBr? VBi? VO?? defect cluster was highly related to the singlet oxygen (1O2) production ability of BiOBr. Meanwhile, the excellent photocatalytic selective oxidation reactions were successfully realized over BiOBr with the VBr? VBi? VO?? defect cluster. In addition, time-dependent defect cluster generation and the associated molecular oxygen activation were discussed.

PROCESS FOR THE PREPARATION OF ORGANIC HALIDES

The present invention provides a halo-de-carboxylation process for the preparation of organic chlorides, organic bromides and mixtures thereof, from their corresponding carboxylic acids, using a chlorinating agent selected from trichloroisocyanuric acid (TCCA), dichloroisocyanuric acid (DCCA), or combination thereof, and a brominating agent.