84388-68-1 Usage
General Description
4,5-Dichlorosalicylaldehyde is a chemical compound with the molecular formula C7H4Cl2O2. It is a derivative of salicylaldehyde and is widely used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and dyes. It is a white to off-white crystalline powder that is sparingly soluble in water and soluble in most organic solvents. 4,5-Dichlorosalicylaldehyde is known for its diverse range of applications, including its use as a precursor in the synthesis of heterocycles, coordination complexes, and ligands for metal-based catalysts. It is also utilized in the production of fragrances and flavors, as well as in the development of materials with potential as antimicrobial and anticancer agents. Additionally, 4,5-Dichlorosalicylaldehyde has been studied for its potential use in analytical chemistry and as a fluorescent probe for the detection of metal ions.
Check Digit Verification of cas no
The CAS Registry Mumber 84388-68-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,3,8 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84388-68:
(7*8)+(6*4)+(5*3)+(4*8)+(3*8)+(2*6)+(1*8)=171
171 % 10 = 1
So 84388-68-1 is a valid CAS Registry Number.
84388-68-1Relevant articles and documents
ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
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Paragraph 0205-0206, (2021/04/17)
A compound of Formula I ( I ), or a pharmaceutically acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
ARYLMETHYLENE AROMATIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
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Paragraph 0232-0233, (2021/04/17)
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group
Chen, Xiao-Yang,Ozturk, Seyma,Sorensen, Erik J.
supporting information, p. 6280 - 6283 (2017/12/08)
The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.
