Welcome to LookChem.com Sign In|Join Free

CAS

  • or
4,5-Dichlorosalicylaldehyde is a chemical compound with the molecular formula C7H4Cl2O2. It is a derivative of salicylaldehyde and is widely used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and dyes. It is a white to off-white crystalline powder that is sparingly soluble in water and soluble in most organic solvents.

84388-68-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 84388-68-1 Structure
  • Basic information

    1. Product Name: 4,5-Dichlorosalicylaldehyde
    2. Synonyms: 4,5-Dichlorosalicylaldehyde
    3. CAS NO:84388-68-1
    4. Molecular Formula: C7H4Cl2O2
    5. Molecular Weight: 191.01146
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 84388-68-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4,5-Dichlorosalicylaldehyde(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4,5-Dichlorosalicylaldehyde(84388-68-1)
    11. EPA Substance Registry System: 4,5-Dichlorosalicylaldehyde(84388-68-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 84388-68-1(Hazardous Substances Data)

84388-68-1 Usage

Uses

Used in Pharmaceutical Industry:
4,5-Dichlorosalicylaldehyde is used as a building block for the preparation of various pharmaceuticals, due to its versatile chemical properties and reactivity.
Used in Agrochemical Industry:
4,5-Dichlorosalicylaldehyde is used as a precursor in the synthesis of agrochemicals, contributing to the development of effective crop protection agents.
Used in Dye Industry:
4,5-Dichlorosalicylaldehyde is used in the production of dyes, taking advantage of its chemical structure to create a range of colorants for various applications.
Used in Synthesis of Heterocycles:
4,5-Dichlorosalicylaldehyde is used as a precursor in the synthesis of heterocycles, which are important in the development of complex organic molecules and have applications in various fields.
Used in Coordination Complexes and Metal-based Catalysts:
4,5-Dichlorosalicylaldehyde is used in the formation of coordination complexes and as ligands for metal-based catalysts, playing a crucial role in catalytic reactions.
Used in Fragrance and Flavor Industry:
4,5-Dichlorosalicylaldehyde is utilized in the production of fragrances and flavors, adding to the diversity of scents and tastes in various consumer products.
Used in Antimicrobial and Anticancer Agents Development:
4,5-Dichlorosalicylaldehyde is studied for its potential use in the development of materials with antimicrobial and anticancer properties, due to its chemical structure and reactivity.
Used in Analytical Chemistry:
4,5-Dichlorosalicylaldehyde has been studied for its potential use in analytical chemistry, particularly as a fluorescent probe for the detection of metal ions, enhancing the sensitivity and selectivity of analytical methods.

Check Digit Verification of cas no

The CAS Registry Mumber 84388-68-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,3,8 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84388-68:
(7*8)+(6*4)+(5*3)+(4*8)+(3*8)+(2*6)+(1*8)=171
171 % 10 = 1
So 84388-68-1 is a valid CAS Registry Number.

84388-68-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,5-dichloro-2-hydroxybenzaldehyde

1.2 Other means of identification

Product number -
Other names 2-hydroxy-4,5-dichloro-benzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:84388-68-1 SDS

84388-68-1Relevant articles and documents

ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS

-

Paragraph 0205-0206, (2021/04/17)

A compound of Formula I ( I ), or a pharmaceutically acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.

ARYL HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS

-

Paragraph 0328-0329, (2021/04/17)

A compound of Formula (I), or a pharmaceutically-acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.

ARYLMETHYLENE AROMATIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS

-

Paragraph 0232-0233, (2021/04/17)

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.

Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles

Guo, Bin,Guo, Shimeng,Huang, Jing,Li, Jingya,Li, Jia,Chen, Qian,Zhou, Xianli,Xie, Xin,Yang, Yushe

, p. 5780 - 5791 (2018/11/06)

GPR40 has become a new potential therapeutic target for the treatment of diabetes due to its role in mediating the enhancement of glucose-stimulated insulin secretion in pancreatic β cells with a low risk of hypoglycemia. As an effort to extend the chemical space and identify structurally distinct GPR40 agonists with improved liver safety, a novel series of fused-ring phenyl propanoic acid analogues were designed. Comprehensive structure-activity relationship studies around novel scaffolds were conducted and led to several analogues exhibited potent GPR40 agonistic activities and high selectivity against other fatty acid receptors. Further evaluation of pharmacokinetic (PK) profiles and in vivo efficacy identified compound 40a with excellent PK properties and significant glucose-lowering efficacy during an oral glucose tolerance test. In addition, compound 40a displayed lower hepatobiliary transporter inhibition and favorable druggability. All results indicate that compound 40a is a promising candidate for further development.

Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group

Chen, Xiao-Yang,Ozturk, Seyma,Sorensen, Erik J.

supporting information, p. 6280 - 6283 (2017/12/08)

The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.

Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models

Cheng, Jianjun,Giguere, Patrick M.,Schmerberg, Claire M.,Pogorelov, Vladimir M.,Rodriguiz, Ramona M.,Huang, Xi-Ping,Zhu, Hu,McCorvy, John D.,Wetsel, William C.,Roth, Bryan L.,Kozikowski, Alan P.

supporting information, p. 578 - 591 (2016/02/05)

A series of novel compounds with two halogen substituents have been designed and synthesized to further optimize the 2-phenylcyclopropylmethylamine scaffold in the quest for drug-like 5-HT2C agonists. Compound (+)-22a was identified as a potent

CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS

-

Paragraph 0273-0275, (2016/08/23)

Disclosed are 2-phenyl-cyclopropylmethanamines which are selective 5-HT(2C) receptor agonists and are used in the treatments of diseases and conditions wherein modulation of 5-HT(2C) receptors provides a benefit, such as obesity and psychiatric disorders.

BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B

-

Paragraph 0114; 0123, (2015/02/25)

Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described (formula 1) together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-alpha and beta) has been presented. In particular, the invention describes a method of inhibiting PI3K isoforms, wherein the compounds are novel structures based on liphagane scaffold with unique boronic acid functionality. The methods and uses thereof are described herein this invention.

BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-alpha AND/OR beta

-

Page/Page column 19; 30, (2013/10/08)

Compounds with unique liphagane meroterpenoid scaffold having boronic acid functionality in the skeleton are described [formula 1] together with pharmacological potential of these compounds as anticancer agents. A method of preparation and inhibiting the activity of phosphoinositide-3-kinase (PI3K-alpha and beta) has been presented. In particular, the invention describes a method of inhibiting PI3K isoforms, wherein the compounds are novel structures based on liphagane scaffold with unique boronic acid functionality. The methods and uses thereof are described herein this invention. The claimed Markush formula is: [Formular 1], Y can be O, NH, NR, S; Representative compounds are: [Compounds A, B, C, D]

WATER-SOLUBLE SHPS AS NOVEL ALKYLATING AGENTS

-

Page 9, (2010/02/09)

The present invention relates to compounds according to the structure (I): Where R is —CH3 or —CH2CH2Cl; R′ is C1-C7 alkyl or —CH2CH2Cl; R2 or R4 is OPOsub

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 84388-68-1