84388-73-8Relevant academic research and scientific papers
Mimetics of the Arg-Gly-Asp Sequence: Synthesis and Studies of the Antiaggregative Properties
Golubovich, V. P.,Gribovskaya, O. V.,Martinovich, V. P.,Rasyuk, E. D.,Rodko, E. V.,Ryabtseva, T. V.
, p. 1249 - 1256 (2021/12/23)
Abstract—: It is known that the Arg-Gly-Asp sequence in the fibrinogen molecule is key in binding to the receptors on the surface of platelets. We searched for the compounds which were able to inhibit the binding and synthesized the following analogs of t
Functionalized 4-hydroxy coumarins: Novel synthesis, crystal structure and DFT calculations
Stefanou, Valentina,Matiadis, Dimitris,Melagraki, Georgia,Afantitis, Antreas,Athanasellis, Giorgos,Igglessi-Markopoulou, Olga,McKee, Vickie,Markopoulos, John
experimental part, p. 384 - 402 (2011/03/22)
A novel short-step methodology for the synthesis in good yields of functionalized coumarins has been developed starting from an activated precursor, the N-hydroxysuccinimide ester of O-acetylsalicylic acid. The procedure is based on a tandem C-acylation-c
