84389-35-5 Usage
Uses
Used in Photolabeling Applications:
2-(dimethylamino)ethyl 4-azidobenzoate is used as a photoaffinity probe for the identification and study of protein interactions. Its azide group allows for covalent binding to target proteins upon activation by UV light, facilitating the investigation of protein functions and interactions within biological systems.
Used in Chemical Biology Studies:
In the field of chemical biology, 2-(dimethylamino)ethyl 4-azidobenzoate serves as a key component in the synthesis of photoaffinity labels. These labels are crucial for elucidating the mechanisms of biological processes and for the discovery of novel bioactive compounds.
Used in Drug Discovery and Development:
2-(dimethylamino)ethyl 4-azidobenzoate has potential applications in drug discovery and development. Its ability to form covalent bonds with target proteins can aid in the design of new drugs with high specificity and affinity for their intended biological targets, potentially leading to more effective therapeutic agents.
Used in the Study of Biological Processes and Mechanisms:
2-(dimethylamino)ethyl 4-azidobenzoate is also utilized in the study of biological processes and mechanisms. By employing 2-(dimethylamino)ethyl 4-azidobenzoate in photoaffinity labeling, researchers can gain insights into the structure and function of proteins, as well as the pathways in which they participate, contributing to a deeper understanding of biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 84389-35-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,3,8 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 84389-35:
(7*8)+(6*4)+(5*3)+(4*8)+(3*9)+(2*3)+(1*5)=165
165 % 10 = 5
So 84389-35-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N4O2/c1-15(2)7-8-17-11(16)9-3-5-10(6-4-9)13-14-12/h3-6H,7-8H2,1-2H3
84389-35-5Relevant academic research and scientific papers
Synthesis of Azaylide-Based Amphiphiles by the Staudinger Reaction
Kishida, Natsuki,Suzuki, Hayate,Toyota, Shinji,Yamashina, Masahiro,Yoshizawa, Michito
, p. 17915 - 17919 (2021/07/09)
Catalyst- and reagent-free reactions are powerful tools creating various functional molecules and materials. However, such chemical bonds are usually hydrolysable or require specific functional groups, which limits their use in aqueous media. Herein, we report the development of new amphiphiles through the Staudinger reaction. Simple mixing of chlorinated aryl azide with a hydrophilic moiety and various triarylphosphines (PAr3) gave rise to azaylide-based amphiphiles NPAr3, rapidly and quantitatively. The obtained NPAr3 formed ca. 2 nm-sized spherical aggregates (NPAr3)n in water. The hydrolysis of NPAr3 was significantly suppressed as compared with those of non-chlorinated amphiphiles nNPAr3. Computational studies revealed that the stability is mainly governed by the decrease in LUMO around the phosphorus atom owing to the o-substituted halogen groups. Furthermore, hydrophobic dyes such as Nile red and BODIPY were encapsulated by the spherical aggregates (NPAr3)n in water.
Sequential dynamic structuralisation by: In situ production of supramolecular building blocks
Yuasa, Hirohiko,Asakura, Kouichi,Banno, Taisuke
supporting information, p. 8553 - 8556 (2017/08/04)
We herein report an example of sequential dynamic higher structuralisation from disordered droplets into higher-ordered structures, resulting in the formation of a hydrogel. This is a potential model for understanding complicated biosystems in which lower-ordered structures evolve into higher-ordered structures that interact with specific molecules.
