84389-35-5 Usage
General Description
2-(dimethylamino)ethyl 4-azidobenzoate is a chemical compound that contains a dimethylaminoethyl group and a 4-azidobenzoate group. It is commonly used in photolabeling and chemical biology studies due to its azide functional group, which can undergo photoaffinity labeling reactions with biological molecules. 2-(dimethylamino)ethyl 4-azidobenzoate is often employed in the synthesis of photoaffinity labels and can be activated by UV light to covalently bind to target proteins, providing a tool for identifying and studying protein interactions. Additionally, 2-(dimethylamino)ethyl 4-azidobenzoate has potential applications in drug discovery and development, as well as in the study of biological processes and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 84389-35-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,3,8 and 9 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 84389-35:
(7*8)+(6*4)+(5*3)+(4*8)+(3*9)+(2*3)+(1*5)=165
165 % 10 = 5
So 84389-35-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N4O2/c1-15(2)7-8-17-11(16)9-3-5-10(6-4-9)13-14-12/h3-6H,7-8H2,1-2H3
84389-35-5Relevant articles and documents
Synthesis of Azaylide-Based Amphiphiles by the Staudinger Reaction
Kishida, Natsuki,Suzuki, Hayate,Toyota, Shinji,Yamashina, Masahiro,Yoshizawa, Michito
, p. 17915 - 17919 (2021/07/09)
Catalyst- and reagent-free reactions are powerful tools creating various functional molecules and materials. However, such chemical bonds are usually hydrolysable or require specific functional groups, which limits their use in aqueous media. Herein, we report the development of new amphiphiles through the Staudinger reaction. Simple mixing of chlorinated aryl azide with a hydrophilic moiety and various triarylphosphines (PAr3) gave rise to azaylide-based amphiphiles NPAr3, rapidly and quantitatively. The obtained NPAr3 formed ca. 2 nm-sized spherical aggregates (NPAr3)n in water. The hydrolysis of NPAr3 was significantly suppressed as compared with those of non-chlorinated amphiphiles nNPAr3. Computational studies revealed that the stability is mainly governed by the decrease in LUMO around the phosphorus atom owing to the o-substituted halogen groups. Furthermore, hydrophobic dyes such as Nile red and BODIPY were encapsulated by the spherical aggregates (NPAr3)n in water.