84454-07-9Relevant academic research and scientific papers
Enantioselective Synthesis of α-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation
Yan, Zhong,Wu, Bo,Gao, Xiang,Chen, Mu-Wang,Zhou, Yong-Gui
, p. 692 - 695 (2016)
A highly enantioselective palladium-catalyzed hydrogenation of a series of linear and cyclic α-iminophosphonates has been achieved, providing efficient access to optically active α-aminophosphonates with up to 99% ee. (Chemical Equation Presented).
Asymmetric synthesis of functionalized tetrasubstituted α-aminophosphonates through enantioselective aza-Henry reaction of phosphorylated ketimines
Vicario, Javier,Ortiz, Pablo,Ezpeleta, José M.,Palacios, Francisco
, p. 156 - 164 (2016/09/09)
Bifunctional Cinchona alkaloid thioureas efficiently catalyze asymmetric nucleophilic addition of nitromethane to ketimines derived from α-aminophosphonic acids to afford tetrasubstituted α-amino-β-nitro-phosphonates. Catalytic hydrogenation of (S)-α-amin
Asymmetric cyanation of a-ketiminophosphonates catalyzed by cinchona alkaloids: Enantioselective synthesis of tetrasubstituted a-aminophosphonic acid derivatives from trisubstituted a-aminophosphonates
Vicario, Javier,Ezpeleta, Jose Mari,Palacios, Francisco
, p. 2641 - 2647 (2013/01/15)
An enantioselective synthesis of tetrasubstituted a-phosphono-a-amino nitriles through asymmetric cyanation of a-ketiminophosphonates catalyzed by Cinchona alkaloids is reported. a-Ket- ACHTUNGTRENUNGiminophosphonates are generated, in a very efficient sy
A Facile Synthesis of O,O-Dialkyl-α-(p-toluenesulphonamido)-benzyl Phosphonates
Varaprasad, I. V. S.,Jaiswal, D. K.
, p. 525 - 527 (2007/10/02)
A series of O,O-dialkyl-α-(p-toluenesulphonamido)benzyl phosphonates have been synthesised by the addition of alkyl phosphites to N-benzylidene-p-toluenesulphonamide.The compounds exhibit chemical shift nonequivalence of prochiral alkoxy groups.Furthermore, on the basis of observed 2JPCH, a preferred conformation with benzylic hydrogen in gauche-disposition to phosphoryl group has been suggested.
