84455-89-0Relevant academic research and scientific papers
Δ2-1,2,4-oxadiazolines by condensation of amidoximes with ketones and aldehydes
Lessel
, p. 383 - 389 (2007/10/02)
Using acetic acid as a solvent, ketones and aromatic aldehydes react with amidoximes 1 to cyclic products, Δ2-1,2,4-oxadiazolines 3. The lack of reactivity in neutral milieu is explained by MNDO calculations. Protonated carbonyl compounds are discussed to be the reactive species.
FORMATION OF 4,5-DIHYDRO-1,2,4-OXADIAZOLES FROM 2-ACYLOXYAMINO OXIMES
Tikhonov, A. Ya.,Belova, N. V.,Volodarskii, L. B.,Gatilov, Yu. V.
, p. 177 - 183 (2007/10/02)
2-Acetoxyamino oximes were obtained by the acylation of 2-hydroxyamino oximes with acetic anhydride.Treatment of 2-acetoxyamino oximes and 2-chloroacetoxyamino oximes with alkali led to rearrangement with the formation of 4,5-dihydro-1,2,4-oxadiazoles.
