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(+)-3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID, commonly known as Carvedilol, is a pharmaceutical compound that belongs to the class of beta-blockers. It is characterized by a tetrahydrocarbazole ring system, a fluorophenylsulfonyl group, and an acetic acid moiety, which collectively contribute to its therapeutic effects. Carvedilol is recognized for its ability to relax blood vessels, slow heart rate, and improve blood flow, thereby reducing blood pressure. Additionally, it exhibits antioxidant and anti-inflammatory properties, making it a versatile medication for cardiovascular health.

844639-57-2

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844639-57-2 Usage

Uses

Used in Cardiovascular Applications:
Carvedilol is utilized as a beta-blocker for the treatment of heart failure and hypertension. It functions by relaxing blood vessels and slowing the heart rate, which enhances blood flow and decreases blood pressure. This medication is particularly beneficial in managing conditions that involve high blood pressure and compromised heart function.
Used in Angina Management:
In the field of cardiology, Carvedilol is used as a therapeutic agent for angina, a condition characterized by chest pain due to insufficient blood flow to the heart. Its ability to improve blood flow and reduce the workload on the heart makes it an effective treatment option for angina patients.
Used in Arrhythmia Treatment:
Carvedilol is also employed in the management of arrhythmias, which are irregular heartbeats that can lead to various complications if left untreated. As a beta-blocker, it helps regulate the heart's rhythm and prevent the occurrence of life-threatening arrhythmias.
Used in Antioxidant and Anti-Inflammatory Therapy:
Beyond its primary cardiovascular applications, Carvedilol is recognized for its antioxidant and anti-inflammatory properties. It can be used in adjunct therapy to combat oxidative stress and inflammation associated with various conditions, thereby contributing to overall health and well-being.
Used in Pharmaceutical Formulations:
Carvedilol is available in various pharmaceutical formulations, including immediate-release and extended-release tablets, allowing for flexible and convenient administration to patients. This versatility in formulation contributes to its widespread use and acceptance in medical practice for cardiovascular conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 844639-57-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,4,6,3 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 844639-57:
(8*8)+(7*4)+(6*4)+(5*6)+(4*3)+(3*9)+(2*5)+(1*7)=202
202 % 10 = 2
So 844639-57-2 is a valid CAS Registry Number.

844639-57-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 9H-Carbazole-9-acetic acid, 3-[[(4-fluorophenyl)sulfonyl]methylamino]-1,2,3,4-tetrahydro-

1.2 Other means of identification

Product number -
Other names 3-[[(4-FLUOROPHENYL)SULFONYL]METHYLAMINO]-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE-9-ACETIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:844639-57-2 SDS

844639-57-2Downstream Products

844639-57-2Relevant academic research and scientific papers

Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist

Ulven, Trond,Kostenis, Evi

, p. 897 - 900 (2007/10/03)

Ramatroban, a thromboxane A2 receptor (TP) antagonist with clinical efficacy in asthma and allergic rhinitis, was recently shown to also antagonize the prostaglandin D2 receptor CRTH2. Here we report that minor structural changes to

COMPOUND EXHIBITING PGD 2 RECEPTOR ANTAGONISM

-

Page 32, (2008/06/13)

A compound having CRTH2 receptor antagonism, represented by the following formula (I). The compound is useful for the treatment of allergic diseases having a relation to eosinophils and the like. A compound of the formula (I): wherein a group represented

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