84494-64-4

Upstream product

• 107-97-1 sarcosine 
• 100-52-7 benzaldehyde 
• 103-67-3 benzyl-methyl-amine 
• 550-58-3 N-methylamino-2 diphenyl-1,2 ethanol erythro 
• 908094-04-2 phenyldiazomethane 
• 84494-64-4 3-methyl-r-2,t-4,c-5-triphenyloxazolidine 
• 550-58-3 DL-threo-2-methylamino-1.2-diphenyl-ethanol 
• 622-29-7 N-Benzylidenemethylamine 
• 71653-79-7 cis-1-methyl-2,3-diphenylaziridine 

Downstream Products

• 84494-64-4 3-methyl-r-2,c-4,t-5-triphenyloxazolidine 

Relevant academic research and scientific papers

Synthesis of 2,4,5-triphenyl-substituted oxazolidine and 2,5-diphenyl-substituted pyrrolidine derivatives

A simple one-pot domino reaction procedure for the stereoselective synthesis of oxazolidines and C2-symmetric pyrrolidines from inexpensive starting materials is described. Azomethine ylides generated in situ by heating a mixture of benzaldehyde and benzylic amines are trapped with dipolarophiles by a 1,3-dipolar cycloaddition reaction. The products represent valuable synthetic building blocks or potential starting materials for the preparation of chiral auxiliaries and are difficult to obtain by other methods.

1,3 DIPOLAR CYCLOADDITIONS OF AZOMETHINE YLIDES WITH AROMATIC ALDEHYDES. SYNTHESES OF 1-OXAPYRROLIZIDINES AND 1,3-OXAZOLIDINES.

Substituted 1-oxapyrrolizidines have been synthetized by cycloaddition of azomethine ylides, generated by aldehydes induced decarboxylation of proline, with carbonyl dipolarophyles.The stereochemistry of the cycloadducts indicate that they arise from the

AZIRIDINES-IV CATALYTIC DECOMPOSITION OF PHENYLDIAZOMETHANE IN SCHIFF'S BASES

Catalytic decomposition of phenyldiazomethane in Schiff's bases is found to proceed via formation of trans-1,3-dipole (azomethine ylide) as an intermediate product.Depending on the size and quantity of the substituents, the ylide undergoes either cyclizat