84499-68-3

Usage

Chemical class

The compound is a purine derivative with an azidoacetate functional group.

Use

It is used as a reagent in organic synthesis and chemical research.

Potential applications

The compound has potential applications in bioconjugation, drug development, and chemical biology.

Biological activity

Its structure suggests that it may have biological activity, making it a potential lead compound for drug discovery.

Click chemistry

The azidoacetate group makes it useful for click chemistry reactions, a powerful tool for bioconjugation and labeling of biomolecules.

Upstream product

• 59277-89-3 acycloguanosine 
• 30426-58-5 2-azidoacetyl chloride 

Downstream Products

• 84499-61-6 9-<<2-(glycyloxy)ethoxy>methyl>guanine hydrochloride 

Relevant academic research and scientific papers

Derivatives of 9-(2-hydroxyethoxymethyl) guanine

Compounds of the general formula STR1 (wherein X represents an oxygen or sulphur atom, R1 represents a hydroxy or amino group, R2 represents a hydrogen atom or a group of formula --CH2 OR3a and R3 and R3a which may be the same or different, each represents an amino acid acyl radical) and physiologically acceptable salts thereof are useful for the treatment of viral infections and have been found to have a surprisingly high water-solubility which renders them of value in the formulation of aqueous pharmaceutical preparations. Processes for preparing the compounds are described.

Synthesis and Antiviral Activity of Water-Soluble Esters of Acyclovir guanine>

Several water-soluble ester derivatives of acyclovir guanine>, i.e., the 2'-O-glycyl-, 2'-O-α-alanyl, 2'-O-β-alanyl- and 2'-O-3-carboxypropionyl esters, were synthesized and evaluated for their antiviral activity in cell cultur