84531-35-1

Basic information

• Product Name: 3-nitro-5,6,7,8-tetrahydroquinoline
• Synonyms: 3-nitro-5,6,7,8-tetrahydroquinoline
• CAS NO: 84531-35-1
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.1879
• Mol File: 84531-35-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-nitro-5,6,7,8-tetrahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-5,6,7,8-tetrahydroquinoline(84531-35-1)
• EPA Substance Registry System: 3-nitro-5,6,7,8-tetrahydroquinoline(84531-35-1)

Safety Data

• Hazardous Substances Data: 84531-35-1(Hazardous Substances Data)

Usage

General Description

3-nitro-5,6,7,8-tetrahydroquinoline is a chemical compound classified under the group of quinolines and isoquinolines. It contains a tetrahydroquinoline moiety, which involves a quinoline ring system where four hydrogen atoms are added. There is a nitro group, a functional group consisting of a nitrogen atom and two oxygen atoms, attached at the third carbon. The structural formula is C9H10N2O2. 3-nitro-5,6,7,8-tetrahydroquinoline is used in various scientific research and chemical synthesis. The compounds' specific physical, chemical properties, and potential hazards or toxicity have not been widely documented and hence should be handled following standard safety procedures for chemical substances.

Upstream product

• 14150-94-8 3,5-dinitro-1-methyl-2-pyridone 
• 108-94-1 cyclohexanone 
• 17758-39-3 1-methyl-5-nitropyrimidin-2(1H)-one 
• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 14080-32-1 5-nitropyrimidine 

Downstream Products

• 151224-99-6 3-Amino-5,6,7,8-tetrahydroquinoline 
• 151224-98-5 3,4-diamino-5,6,7,8-tetrahydroquinoline 

Relevant articles and documents

Synthesis, Characterization, and Rapid Cycloadditions of 5-Nitro-1,2,3-triazine

The synthesis, characterization, and a study of the cycloaddition reactions of 5-nitro-1,2,3-triazine (3) are reported. The electron-deficient nature of 3 permits rapid cycloaddition with a variety of electron-rich dienophiles, including amidines, enamines, enol ethers, ynamines, and ketene acetals in high to moderate yields. 1H NMR studies of a representative cycloaddition reaction between 3 and an amidine revealed a remarkable reaction rate and efficiency (1 mM, 3CN, 23 °C, >95%).

Nitropyrimidinones; synthetic equivalents of diformylamine and nitromalonaldehyde

Reactions of two isomeric nitropyrimidinones with bidentate enolate anions were studied. When 3-methyl-5-nitropyrimidin-4(3H)-one (1) was employed, ring transformation proceeded to give pyridin-4(1H)-ones 3 functionalized at the 3- or 5-positions. This pyrimidin-4-one 1 behaved as an activated diformylamine HN(CHO)2. 1-Methyl-5-nitropyrimidin-2(1H)-one (2) afforded polyfunctionalized bicyclo[3.3.1]nonene derivatives 7 and 8 and/or p-nitrophenol derivatives 9. In this case, pyrimidin-2-one 2 acted as the synthetic equivalent of unstable O2NCH(CHO)2. These two nitropyrimidinones are valuable intermediates for the synthesis of polyfunctionalized compounds.

INVERSE ELECTRON DEMAND DIELS-ALDER REACTIONS OF 5-NITROPYRIMIDINE WITH ENAMINES. SYNTHESIS OF 3-NITROPYRIDINE DERIVATIVES

The reaction of cyclic and non-cyclic enamines with 5-nitropyrimidine has been studied.Many enamines react in an inverse electron-demand Diels-Alder reaction, leading to the formation of 3-nitropyridines.N,S-ketene acetals were also found to react with 5-nitropyrimidines.The mechanism of the reaction will be discussed.