84547-63-7

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Chloromethyl-1-methylpyrazole is used as a key intermediate in the synthesis of pharmaceuticals for its ability to modulate biological targets and contribute to the development of new therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 5-Chloromethyl-1-methylpyrazole is utilized as a building block in the production of various agrochemical compounds, enhancing their effectiveness in pest control and crop protection.
Used in Organic Synthesis:
5-Chloromethyl-1-methylpyrazole serves as a reagent in organic synthesis, facilitating the introduction of the pyrazole moiety into complex molecules and expanding the scope of chemical reactions.
Used in Medicinal Chemistry and Drug Discovery:
In the field of medicinal chemistry, 5-Chloromethyl-1-methylpyrazole is employed as a promising candidate for drug discovery, owing to its potential to modulate biological targets and contribute to the development of innovative therapeutic agents.
Used in the Production of Heterocyclic Compounds:
5-Chloromethyl-1-methylpyrazole is utilized as a versatile building block in the synthesis of various heterocyclic compounds, which are essential components in numerous pharmaceuticals, agrochemicals, and other organic compounds.

Upstream product

• 16034-46-1 1-methyl-1H-pyrazole-5-carboxylic acid 
• 84547-61-5 (1-methyl-1H-pyrazol-5-yl)methanol 

Downstream Products

• 1071814-43-1 2-(1-methyl-1H-pyrazol-5-yl)acetonitrile 
• 1607023-01-7 5-(4-chloro-3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1607023-26-6 5-(4-chloro-3-isopropoxyphenyl)-3-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1607023-28-8 5-(3-ethoxy-4-fluorophenyl)-3-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1607023-29-9 5-(4-fluoro-3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1607023-51-7 5-(3,4-dichlorophenyl)-3-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidin-7(4H)-one 
• 1071814-23-7 2-(4-bromo-1-methyl-1H-pyrazol-5-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}acetamide 
• 1071814-24-8 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-2-(4-fluoro-1-methyl-1H-pyrazol-5-yl)acetamide 
• 1071814-22-6 2-(4-chloro-1-methyl-1H-pyrazol-5-yl)-N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}acetamide 
• 1071814-21-5 N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-2-(1-methyl-1H-pyrazol-5-yl)acetamide 
• 1071814-44-2 2-(1-methyl-1H-pyrazol-5-yl)acetic acid 

Relevant academic research and scientific papers

PYRROLO [2,3-B]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS

N-(3-Substituted thiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides and N-(3-substituted oxazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides (I) and (II) are disclosed. The compounds activate Yap and inhibit Lats kinases. They are therefore useful for treating hearing loss.

TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE

Provided are quinoline carboxamide and quinoline carbonitrile compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1, R 2, L, X 1, X 2, and X 3, are as defined herein. The compounds of the invention, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising them, are useful as non-competitive mGluR2 antagonists, or mGluR2 negative allosteric modulators (NAMs), and may be useful in methods of treating a person in need thereof for diseases or disorders in which the mGluR2-NAM receptor plays a causative role, such as Alzheimer's disease, cognitive impairment, schizophrenia and other mood disorders, pain disorders and sleep disorders.

HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK

Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.

PYRAZOLE DERIVATIVES AS P2X7 MODULATORS

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R1 represents C1-6 alkyl or C3-6 cycloalkyl, either of which is optionally substituted with 1, 2 or 3 ha