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Z-Ile-Tyr-Pro-OH, also known as N-benzyloxycarbonyl-isoleucine-tyrosine-proline, is a peptide compound consisting of three amino acids: isoleucine, tyrosine, and proline. The "Z" prefix indicates the presence of a benzyloxycarbonyl (Z) protecting group, which is commonly used in peptide synthesis to prevent unwanted side reactions. This specific sequence of amino acids is of interest in the field of biochemistry and pharmaceuticals, as it may exhibit unique biological activities or serve as a building block for the development of new drugs. The protective Z group is crucial for maintaining the integrity of the peptide during synthesis, ensuring that the final product is stable and retains its desired properties.

84552-65-8

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84552-65-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84552-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,5 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 84552-65:
(7*8)+(6*4)+(5*5)+(4*5)+(3*2)+(2*6)+(1*5)=148
148 % 10 = 8
So 84552-65-8 is a valid CAS Registry Number.

84552-65-8Relevant academic research and scientific papers

4-Methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr): a New Amino and Imidazole Protecting Group in Peptide Synthesis

Wakimasu, Mitsuhiro,Kitada, Chieko,Fujino, Masahiko

, p. 2766 - 2779 (2007/10/02)

The 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group was introduced as a protecting group for the amino function, especially the ε-amino function of lysine, and the imidazole ring of histidine.The Nε-Mtr group was removable by dilute methanesulfonic acid-containing trifluoroacetic acid-thioanisole, but was stable to trifluoroacetic acid or catalytic hydrogenation.The Nim-Mtr group was removable by trifluoroacetic acid-dimethylsulfide or 1-hydroxybenzotriazole, but was more stable than the Nim-Tos or the Nim-Mbs group with triethylamine.To examine the usefulness of the Mtr group as a protecting group for use in peptide synthesis, mastoparan X and chicken gastrin releasing peptide (c-GRP) were synthesized, and this group was found to be very convenient for general solution synthesis.In particular, the introduction of Lys(Mtr) made possible a new strategy in peptide synthesis.Keywords-4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); Nε-4-methoxy-2,3,6-trimethylbenzenesulfonyllysine; Nim-4-methoxy-2,3,6-trimethylbenzenesulfonylhistidine; methanesulfonic acid-trifluoroacetic acid-thioanisole deprotection; trifluoroacetic acid-dimethylsulfide deprotection; mastoparan X; chicken gastrin releasing peptide

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