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"Z-Ile-Tyr-Pro-Arg(Pme)-Gly-OBut" is a peptide sequence consisting of seven amino acids. It starts with Z-Ile (Z-Isoleucine), followed by Tyr (Tyrosine), Pro (Proline), Arg(Pme) (Arginine with a p-methoxybenzyl protecting group), Gly (Glycine), and ends with OBut (tert-butyloxycarbonyl protecting group). This sequence is a protected peptide, meaning that the Arginine and the C-terminus are masked with protecting groups to prevent unwanted side reactions during synthesis. The protecting groups are crucial in peptide synthesis to ensure that the peptide bonds form correctly and that the final product has the desired structure. Once the peptide is synthesized, the protecting groups are removed to reveal the active peptide. This particular sequence is of interest in peptide chemistry and may have applications in drug development or as a research tool in biological studies.

84552-67-0

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84552-67-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 84552-67-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,5 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 84552-67:
(7*8)+(6*4)+(5*5)+(4*5)+(3*2)+(2*6)+(1*7)=150
150 % 10 = 0
So 84552-67-0 is a valid CAS Registry Number.

84552-67-0Downstream Products

84552-67-0Relevant academic research and scientific papers

4-Methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr): a New Amino and Imidazole Protecting Group in Peptide Synthesis

Wakimasu, Mitsuhiro,Kitada, Chieko,Fujino, Masahiko

, p. 2766 - 2779 (2007/10/02)

The 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group was introduced as a protecting group for the amino function, especially the ε-amino function of lysine, and the imidazole ring of histidine.The Nε-Mtr group was removable by dilute methanesulfonic acid-containing trifluoroacetic acid-thioanisole, but was stable to trifluoroacetic acid or catalytic hydrogenation.The Nim-Mtr group was removable by trifluoroacetic acid-dimethylsulfide or 1-hydroxybenzotriazole, but was more stable than the Nim-Tos or the Nim-Mbs group with triethylamine.To examine the usefulness of the Mtr group as a protecting group for use in peptide synthesis, mastoparan X and chicken gastrin releasing peptide (c-GRP) were synthesized, and this group was found to be very convenient for general solution synthesis.In particular, the introduction of Lys(Mtr) made possible a new strategy in peptide synthesis.Keywords-4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); Nε-4-methoxy-2,3,6-trimethylbenzenesulfonyllysine; Nim-4-methoxy-2,3,6-trimethylbenzenesulfonylhistidine; methanesulfonic acid-trifluoroacetic acid-thioanisole deprotection; trifluoroacetic acid-dimethylsulfide deprotection; mastoparan X; chicken gastrin releasing peptide

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