84570-84-3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 2393-23-9 4-methoxy-benzylamine 
• 84570-97-8 6-Chloro-2-(4-methoxy-phenyl)-4-phenyl-1,2,3,4-tetrahydro-quinazoline 

Relevant academic research and scientific papers

A new triazine-cored covalent organic polymer for catalytic applications

A triazine based covalent organic polymer (CC-TAPT-COP) was designed and synthesized via nucleophilic substitution reaction between 1,3,5-tris-(p-aminophenyl) triazine and cyanuric chloride under refluxing conditions with bottom-up approach. The structura

Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines

The in situ formed ruthenium catalytic system ([Ru]/L) was found to be highly selective for the dehydrogenative coupling reaction of 2-aminophenyl ketones with amines to form quinazoline products. The deaminative coupling reaction of 2-aminobenzamides with amines led to the efficient formation of quinazolinone products. The catalytic coupling method provides an efficient synthesis of quinazoline and quinazolinone derivatives without using any reactive reagents or forming any toxic byproducts.

Synthesis of quinazolines over recyclable Fe3O4@SiO2-PrNH2-Fe3+ nanoparticles: A green, efficient, and solvent-free protocol

A practical and efficient method is developed for efficient synthesis of quinazoline derivatives through condensation reaction of 2-aminoaryl ketone, an aldehyde, and ammonium acetate, over magnetic Fe3O4@SiO2-PrNH2/

Efficient synthesis of quinazoline derivatives catalyzed by flourinated alcohol

A facile and efficient protocol is reported for the synthesis of quinazoline derivatives via a one-pot multicomponent reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes and ammonium acetate using 1,1,1,3,3,3-hexafluoroisopropanol (HFIP). The use

A new and facile CuCl2·2H2O-catalyzed one-pot three-component synthesis for quinazolines

A new and facile CuCl2·2H2O-catalyzed one-pot three-component synthesis for quinazolines has been developed. A mixture of readily available 2-amino-5-chlorobenzophenones, substituted benzaldehydes, ammonium acetate, and CuCl2/s

Recyclable graphite oxide promoted efficient synthesis of 2-phenyl quinazoline derivatives in the presence of TBHP as an oxidant

A novel and efficient protocol for the synthesis of 2-phenyl quinazoline derivatives is developed by recyclable graphite oxide as a catalyst, devoid of moisture sensitive metal catalysts and corrosive acidic reagents. This new procedure has afforded the desired products in good to excellent yields. The graphite oxide can be synthesized by a simple adoptable procedure from inexpensive and readily available graphite and is recoverable and reusable up to four cycles, without any loss of activity.

Catalyst-free synthesis of quinazoline derivatives using low melting sugar-urea-salt mixture as a solvent

Low melting mixture of maltose-dimethylurea (DMU)-NH4Cl was found to be an inexpensive, non-toxic, easily biodegradable and effective reaction medium in the catalyst-free synthesis of quinazoline derivatives. This simple and efficient method fu

An efficient protocol for the synthesis of 2-phenylquinazolines catalyzed by ceric ammonium nitrate (CAN)

A facile and efficient method for the synthesis of 2-phenylquinazolines has been developed from 2-aminobenzophenones and benzylamines catalyzed by ceric ammonium nitrate (CAN)-TBHP in acetonitrile. The corresponding 2-phenylquinazolines were obtained in good to excellent yields. Georg Thieme Verlag Stuttgart - New York.

Ecofriendly and efficient one-pot procedure for the synthesis of quinazoline derivatives catalyzed by an acidic ionic liquid under aerobic oxidation conditions

A three-component condensation reaction between 2-aminobenzophenone derivatives, formaldehyde or aromatic aldehydes, and ammonium acetate efficiently provides substituted quinazolines in a one-pot reaction in the presence of Bronsted acidic ionic liquid, 1-methylimidazolium triflouroacetate ([Hmim]TFA), in conjunction with aerobic oxidation. The ionic liquid was separated from the reaction mixture by simple extraction and was recycled three times without considerable loss in activity. Copyright Taylor & Francis Group, LLC.