845728-26-9

Basic information

• Product Name: 5-Thiazolidinone, 4-[(4-methoxyphenyl)methylene]-3-phenyl-2-(phenylimino)-
• CAS NO: 845728-26-9
• Molecular Formula: C23H18N2O2S
• Molecular Weight: 386.474
• Mol File: 845728-26-9.mol

Chemical Properties

• CAS DataBase Reference: 5-Thiazolidinone, 4-[(4-methoxyphenyl)methylene]-3-phenyl-2-(phenylimino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolidinone, 4-[(4-methoxyphenyl)methylene]-3-phenyl-2-(phenylimino)-(845728-26-9)
• EPA Substance Registry System: 5-Thiazolidinone, 4-[(4-methoxyphenyl)methylene]-3-phenyl-2-(phenylimino)-(845728-26-9)

Safety Data

• Hazardous Substances Data: 845728-26-9(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 83507-17-9 3-phenyl-2-phenyliminothiazolidin-5-one 
• 102-08-9 N,N-diphenylthiourea 

Relevant articles and documents

Synthesis of some new thiazolidin-5-one derivatives of pharmaceutical interest

Condensation of thiazolidin-5-one derivative 1 with different aromatic aldehydes gave the corresponding arylidenes 2a-e. Compound 2e was reacted with urea and thiourea to give the corresponding thiazolo[5,4-d]pyrimidine derivatives 3a,b, respectively. Treatment of compound 1 with phenyl isothiocyanate in basic DMF gave the nonisolable potassium salt of the adduct 4, which underwent heterocyclization upon treatment with chloroacetyl chloride and phenacyl bromide to give the corresponding [2,4′] bisthiazolidinylidenes 5 and 8. Moreover, the reactions of compound 1 with a variety of reagents, e.g., ninhydrin and isatin, were investigated. The structures of these compounds were established by analytical and spectral data.