845882-08-8

Upstream product

• 672-31-1 3-hydroxy(pentafluorosulfanyl)benzene 
• 534-17-8 caesium carbonate 
• 190367-50-1 4-fluoro-5-methanesulfonyl-2-methyl-benzoic acid methyl ester 
• 176308-97-7 4-bromo-5-methanesulfonyl-2-methyl-benzoic acid methyl ester 

Relevant academic research and scientific papers

Pentafluorosulfanylphenyl-substituted benzoylguanidines, method for the production thereof, their use as a medicament or diagnostic agent, and a medicament containing these compounds

The invention relates to pentafluorosulfanylphenyl-substituted benzoylguanidines of the formula I: and a process for preparing a compound of the formula I and/or the pharmaceutically acceptable salts thereof.

PENTAFLUOROSULFANYLPHENYL-SUBSTITUTED BENZOYLGUANIDINES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC AGENT, AND A MEDICAMENT CONTAINING THESE COMPOUNDS

The invention relates to pentafluorosulfanylphenyl-substituted benzoylguanidines, to a method for the production thereof, to their use as a medicament or diagnostic agent, and to a medicament containing these compounds. These pentafluorosulfanylphenyl-sub

ORTHO-SUBSTITUTED PENTAFLUOROSULFANYL BENZENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS SYNTHESIS INTERMEDIATES

The invention relates to pentafluorosulfanyl benzenes of formula (I) in which R1 to R5 have the meanings as cited in the claims, which depict valuable intermediates, e.g. for producing medicaments, diagnostic agents, liquid crystals, pesticides, herbicides, fungicides, nematicides, parasiticides, insecticides, acaricide, arthropodicides and polymers.

Pentafluorosulfanylphenyl-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic aid, and medicament comprising them

Pentafluorosulfanylphenyl-substituted benzoylguanidines of the formulae I and II in which R1, R1′, R2, R2′, R3, R3′, R4 and X have the meanings indicated in the claims, are suitable as antiarrhythmic medicaments with a cardioprotective component for the prophylaxis of infarction and treatment of infarction and for the treatment of angina pectoris. They also inhibit preventively the pathophysiological processes associated with the development of ischemia-induced damage, especially in the triggering of ischemia-induced cardiac arrhythmias.