846038-45-7

Basic information

• Product Name: Quinoline, 5-bromo-, 1-oxide
• CAS NO: 846038-45-7
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.057
• Mol File: 846038-45-7.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Quinoline, 5-bromo-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 5-bromo-, 1-oxide(846038-45-7)
• EPA Substance Registry System: Quinoline, 5-bromo-, 1-oxide(846038-45-7)

Safety Data

• Hazardous Substances Data: 846038-45-7(Hazardous Substances Data)

Upstream product

• 4964-71-0 5-bromoquinoline 

Downstream Products

• 99455-13-7 5-bromo-2-chloroquinoline 
• 1092304-90-9 5-bromoquinoline-2-carbonitrile 
• 1404431-45-3 5-bromo-1-(4-methoxybenzyl)quinolin-2(1H)-one 
• 1404431-46-4 7-bromo-3-(4-methoxybenzyl)-3,7b-dihydro-1H-cyclopropa[c]quinolin-2(1aH)-one 
• 1632293-77-6 C₃₂H₁₄BBrF₁₅N 
• 1423778-39-5 5-bromo-2-(phenylethynyl)quinoline 
• 99455-06-8 5-bromo-2-methoxyquinoline 
• 4964-71-0 5-bromoquinoline 
• 1618682-84-0 5-bromo-2-(4-(ethylthio)-2,3,5,6-tetrafluorophenyl)quinoline 
• 1345014-93-8 4-[(1-oxidoquinolin-5-yl)amino]-2-phenyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one 

Relevant articles and documents

IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS

The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.

RhIII-Catalyzed Straightforward Synthesis of Benzophenanthroline and Benzophenanthrolinone Derivatives using Anthranils

An efficient pot-economic and step-economic RhIII-catalyzed site-selective direct amination/annulation strategy was developed for the synthesis of benzophenanthroline derivatives using quinoline N-oxides and anthranils. The method was further extended to the synthesis of nitrogen-containing extended π-conjugated benzophenanthrolinone derivatives. Late-stage functionalizations of cinchonidine and cinchophen derivatives and synthesis of a bioactive quinolino-indole were achieved.

Synthesis of 2-Alkenylquinoline by Reductive Olefination of Quinoline N-Oxide under Metal-Free Conditions

Synthesis of 2-alkenylquinoline by reductive olefination of quinoline N-oxide under metal-free conditions is disclosed. Practically, the reaction could be performed with quinoline as starting material via a one-pot, two-step process. A possible mechanism is proposed that involves a sequential 1,3-dipolar cycloaddition and acid-assisted ring opening followed by a dehydration process.