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CAS

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84633-29-4

Eurycomanone, a cytotoxic compound derived from Eurycoma Longifolia Jack, has gained significant attention for its potential applications in various fields. This bioactive compound possesses the ability to target and suppress the growth of cancer cells, making it a promising candidate for pharmaceutical and therapeutic purposes.

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  • 84633-29-4 Structure

  • Basic information

    1. Product Name: EURYCOMANONE
    2. Synonyms: EURYCOMANONE;11,2o-epoxy-1,11,12,14,15-pentahydroxy-13(21)-diene-(1-picrasa-16-dione;11-beta,12-alpha,15-beta)-betdihydrate;pasakbumin-a;11β,20-Epoxy-1β,11,12α,14,15β-pentahydroxypicrasa-3,13(21)-diene-2,16-dione;NSC 339187;(1beta,8xi,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-11,20-epoxypicrasa-3,13(21)-diene-2,16-dione;Eurycoma longifolia
    3. CAS NO:84633-29-4
    4. Molecular Formula: C20H28O11
    5. Molecular Weight: 444.43
    6. EINECS: N/A
    7. Product Categories: Apoptosis, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 84633-29-4.mol

  • Chemical Properties

    1. Melting Point: 273-285℃ (methanol ethyl ether )
    2. Boiling Point: 669.5°C at 760 mmHg
    3. Flash Point: 239.9°C
    4. Appearance: /
    5. Density: 1.63g/cm3
    6. Vapor Pressure: 8.66E-21mmHg at 25°C
    7. Refractive Index: 1.684
    8. Storage Temp.: -20°C Freezer
    9. Solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Pyridine (Slightly, Son
    10. PKA: 11.29±0.70(Predicted)
    11. CAS DataBase Reference: EURYCOMANONE(CAS DataBase Reference)
    12. NIST Chemistry Reference: EURYCOMANONE(84633-29-4)
    13. EPA Substance Registry System: EURYCOMANONE(84633-29-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 84633-29-4(Hazardous Substances Data)

84633-29-4 Usage

Uses

Used in Pharmaceutical Industry:
Eurycomanone is used as a cytotoxic agent for its ability to effectively target and eliminate various cancer cell lines. Its potency in suppressing the expression of lung cancer cell tumor markers, such as prohibitin, annexin 1, and endoplasmic reticulum protein 28, highlights its potential in combating lung cancer.
Furthermore, Eurycomanone is used as an apoptosis inducer in human cervical carcinoma cells. It achieves this by up-regulating the expression of p53, a crucial protein involved in the regulation of the cell cycle and apoptosis. This property of Eurycomanone makes it a valuable component in the development of novel therapeutic strategies for cervical cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 84633-29-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,6,3 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 84633-29:
(7*8)+(6*4)+(5*6)+(4*3)+(3*3)+(2*2)+(1*9)=144
144 % 10 = 4
So 84633-29-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18?,19-,20+/m0/s1

84633-29-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name eurycomanone

1.2 Other means of identification

Product number -
Other names EURYCOMANONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:84633-29-4 SDS

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