84657-23-8

Upstream product

• 84657-20-5 2-chloro-4-methoxy-5-methylbenzyl chloride 
• 32723-67-4 3-methyl-4-anisaldehyde 
• 40794-04-5 1-chloro-3-methoxy-4-methylbenzene 
• 84657-21-6 2-chloro-4-methoxy-5-methylbenzyl acetate 
• 84657-22-7 2-chloro-4-methoxy-5-methylbenzyl alcohol 

Downstream Products

• 94169-55-8 2-chloro-3',4-dimethoxy-2',5-dimethylstilbene 
• 94169-56-9 2-chloro-3',4-dimethoxy-2',5-dimethylstilbene 
• 84657-24-9 2-chloro-4-hydroxy-5-methylbenzaldehyde 
• 84657-25-0 2-Chloro-4-isopropoxy-5-methylbenzaldehyde 
• 84657-33-0 2-chloro-4-isopropoxy-3'-methoxy-2',5-dimethylstilbene 
• 84657-33-0 2-chloro-4-isopropoxy-3'-methoxy-2',5-dimethylstilbene 
• 84685-52-9 2-chloro-4-isopropoxy-3'-methoxy-2',5-dimethylstilbene 
• 54278-82-9 micandrol-A 
• 54278-83-0 micandrol-B 
• 1023717-33-0 C₁₁H₁₂ClNO₃ 

Relevant academic research and scientific papers

Monodentate Transient Directing Group Enabled Pd-Catalyzed Ortho-C-H Methoxylation and Chlorination of Benzaldehydes

We report Pd-catalyzed ortho-C-H methoxylation and chlorination of benzaldehydes by employing monodentate transient directing groups (TDGs) as an alternative strategy to bidentate TDGs. More importantly, a single crystal of benzaldehyde imine ortho-cyclopalladium intermediate was successfully obtained, and its structure was unambiguously determined by X-ray diffraction, which clearly showed that it was a binuclear palladium species bridged by a pyridone ligand. The utility of this approach was further demonstrated through the synthesis of key intermediates of natural products and drugs.

Phenanthrene Synthesis: The Synthesis of Juncunone and the Micandrols-A, B, E, and F

The synthesis of the naturally occurring phenanthrenes micandrol-A (1,7-dimethylphenanthrene-2,6-diol) (1), micandrol-B (9,10-dihydro-1,7-dimethylphenanthrene-2,6-diol) (2), micandrol-E (7-methoxy-1,2-dimethylphenanthrene-6-ol) (3), micandrol-F (9,10-dihy