84666-27-3

Upstream product

• 18193-09-4 2-(p-tolyl)-6-methoxy-4-quinolinecarboxylic acid 
• 104-94-9 4-methoxy-aniline 
• 104-87-0 4-methyl-benzaldehyde 
• 84666-28-4 4-Chloromethyl-6-methoxy-2-p-tolyl-quinoline 

Downstream Products

• 117839-37-9 6-methoxy-2-(p-tolyl)quinoline 
• 117839-39-1 6-methoxy-4-methyl-2-(p-tolyl)quinoline 
• 112500-20-6 6-Methoxy-2-p-tolyl-quinoline-4-carbaldehyde 
• 112500-23-9 6-Methoxy-4-oxiranyl-2-p-tolyl-quinoline 
• 112500-27-3 2-Hexylsulfanyl-1-(6-methoxy-2-p-tolyl-quinolin-4-yl)-ethanol 
• 112500-28-4 1-(6-Methoxy-2-p-tolyl-quinolin-4-yl)-2-piperidin-1-yl-ethanol 
• 112500-29-5 1-(6-Methoxy-2-p-tolyl-quinolin-4-yl)-2-thiomorpholin-4-yl-ethanol 
• 84666-29-5 2-(6-Methoxy-2-p-tolyl-quinolin-4-ylmethyl)-isothiourea 

Relevant academic research and scientific papers

Synthesis and Photocleavage of Quinoline Methyl Ethers: A Mild and Efficient Method for the Selective Protection and Deprotection of the Alcohol Functionality

The synthesis and photocleavage of quinolinyl methyl ether-protected alcohols is reported in this study. A variety of quinoline methyl chlorides were synthesized, and protection of the various alcohols was performed via a substitution reaction in the presence of a strong base. Photocleavage of the quinolinyl methyl ether moiety proceeded under visible light with the formation of the charged quinolinyl radical intermediate through a single-electron transfer in the presence of a photosensitizer dye leading to the deprotected alcohol in excellent yields. The utility of triethylamine as a sacrificial reductant and d-sorbitol as a radical scavenger were also investigated in this study.

Approaches to a photocleavable protecting group for alcohols

A new protecting group for the alcohol functionality was devised and shown to be removed photochemically under ultraviolet light in the presence of a radical scavenger in high yields.

Sulfur-Containing 2-Arylquinolinemethanols as Potential Antimalarials

The synthesis and antimalarial activity of six new 2-arylquinoline-4-methanols is described.The compounds bearing a sulfur were prepared to determine if antimalarial activity can be retained while photoreactivity and phototoxicity is diminished by such su

A NEW PHOTOCHEMICALLY REMOVABLE PROTECTING GROUP FOR AMINES

A new arylmethylsulfonyl chloride reacts with secondary or primary amines to give sulfonamides which can be photochemically cleaved, making it suitable for use as a photoremovable protecting group.