18193-09-4

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 104-94-9 4-methoxy-aniline 
• 127-17-3 2-oxo-propionic acid 
• 39755-95-8 5-methoxyisatine 
• 122-00-9 para-methylacetophenone 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 117839-37-9 6-methoxy-2-(p-tolyl)quinoline 
• 84666-27-3 2-(p-tolyl)-6-methoxy-4-quinolinemethanol 
• 117839-39-1 6-methoxy-4-methyl-2-(p-tolyl)quinoline 
• 112500-20-6 6-Methoxy-2-p-tolyl-quinoline-4-carbaldehyde 
• 84666-29-5 2-(6-Methoxy-2-p-tolyl-quinolin-4-ylmethyl)-isothiourea 
• 112500-29-5 1-(6-Methoxy-2-p-tolyl-quinolin-4-yl)-2-thiomorpholin-4-yl-ethanol 
• 112500-28-4 1-(6-Methoxy-2-p-tolyl-quinolin-4-yl)-2-piperidin-1-yl-ethanol 
• 112500-27-3 2-Hexylsulfanyl-1-(6-methoxy-2-p-tolyl-quinolin-4-yl)-ethanol 
• 112500-23-9 6-Methoxy-4-oxiranyl-2-p-tolyl-quinoline 

Relevant academic research and scientific papers

Synthesis and molecular dynamic simulation studies of novel N-(1-benzylpiperidin-4-yl) quinoline-4-carboxamides as potential acetylcholinesterase inhibitors

A new series of N-(1-benzylpiperidin-4-yl) quinoline-4-carboxamide derivatives was designed and synthesized as potential acetylcholinesterase inhibitors. The compounds were characterized by nuclear magnetic resonance, infrared and mass spectrometry. In th

Synthesis and Photocleavage of Quinoline Methyl Ethers: A Mild and Efficient Method for the Selective Protection and Deprotection of the Alcohol Functionality

The synthesis and photocleavage of quinolinyl methyl ether-protected alcohols is reported in this study. A variety of quinoline methyl chlorides were synthesized, and protection of the various alcohols was performed via a substitution reaction in the presence of a strong base. Photocleavage of the quinolinyl methyl ether moiety proceeded under visible light with the formation of the charged quinolinyl radical intermediate through a single-electron transfer in the presence of a photosensitizer dye leading to the deprotected alcohol in excellent yields. The utility of triethylamine as a sacrificial reductant and d-sorbitol as a radical scavenger were also investigated in this study.

Synthesis, molecular docking and anti-inflammatory screening of novel quinoline incorporated pyrazole derivatives using the Pfitzinger reaction II

In continuation of our study of novel quinolines with anti-inflammatory activity using the Pfitzinger reaction, several new quinoline derivatives were synthesized and tested for their anti-inflammatory and ulcerogenic effect. A docking study on the COX-2

Approaches to a photocleavable protecting group for alcohols

A new protecting group for the alcohol functionality was devised and shown to be removed photochemically under ultraviolet light in the presence of a radical scavenger in high yields.

Sulfur-Containing 2-Arylquinolinemethanols as Potential Antimalarials

The synthesis and antimalarial activity of six new 2-arylquinoline-4-methanols is described.The compounds bearing a sulfur were prepared to determine if antimalarial activity can be retained while photoreactivity and phototoxicity is diminished by such su

A NEW PHOTOCHEMICALLY REMOVABLE PROTECTING GROUP FOR AMINES

A new arylmethylsulfonyl chloride reacts with secondary or primary amines to give sulfonamides which can be photochemically cleaved, making it suitable for use as a photoremovable protecting group.