84671-76-1Relevant academic research and scientific papers
Copper-catalyzed three-component: N -alkylation of quinazolinones and azoles
Deng, Guo-Jun,Huang, Huawen,Ji, Xiaochen,Wang, Chunlian
supporting information, p. 1200 - 1204 (2022/02/21)
A Cu-catalyzed three-component N-alkylation coupling reaction of N-heteroarenes with methyl ketones and DMPA as a carbon source has been developed. Using methyl ketones as alkylation reagents and DMPA (N,N′-dimethylpropionamide) as a carbon source, the re
SYNTHESIS AND ANALGETIC EFFICIENCY OF SOME OXY AND OXO DERIVATIVES OF 4(3H)-QUINAZOLINONE
Fisnerova, Ludmila,Brunova, Bohumila,Kocfeldova, Zuzana,Tikalova, Jana,Maturova, Eva,Grimova, Jaroslava
, p. 2373 - 2381 (2007/10/02)
A series of 3-substituted 4(3H)-quinazolinone derivatives have been prepared by alkylation of 4(3H)-quinazolinone with halogenoethers, halogenoketones, and Mannich bases, and the products have been tested for analgetic effects.The most interesting represe
EXTRUSION REACTIONS-VI. TRANSFORMATIONS OF BETA(4-QUINAZOLINYLTHIO)KETONES TO 3-(BETA KETOALKYL)-4(3H)-QUINAZOLONE DERIVATIVES
Singh, Harjit,Deep, Kanwal
, p. 4937 - 4940 (2007/10/02)
4-(4-Quinazolinylthio)-butan-2-one and 3-(4-quinazolinylthio) propiophenone (4, R=CH3, C6H5) with POCl3 give 3-(3-oxobutyl)-4(3H)-quinazolone and 3-(2-benzoylethyl)-4(3H)-quinazolone (7, R=CH3, C6H5, X=O) via S N rearrangement followed by =C=S to =C=O conversion.Non-protic heterocyclic thioamides undergo similar oxidation.
A Novel Phosphorus Oxychloride Induced Conversion of β-(4-Quinazolinylthio) Ketones into β- Ketones
Bal, Mohinder S.,Deep, Kanwal,Singh, Harjit
, p. 805 - 806 (2007/10/02)
β-(4-Quinazolinylthio)ketones have been converted into β- ketones on refluxing their solutions in phosphorus oxychloride.
