84671-79-4Relevant articles and documents
Potential Hypolipidemic Agents: Part I-Synthesis and Hypolipidemic Activity of Some 4-(2,5-Substituted oxazole-4-yl)phenoxyalkanoic Acid Derivatives
Shridhar, D. R.,Ram, Bhagat,Sarma, C. R.,Saxena, N. K.
, p. 860 - 864 (2007/10/02)
A series of 4-(2-aryl-5-alkyl-aryloxazol-4-yl)phenoxyalkanoic acid derivatives (VI, 1-32) have been synthesised by O-alkylation of the corresponding 2-aryl-4-(4-hydroxyphenyl)-5-alkyl/aryloxazoles (Va-g) and evaluated for their hypolipidemic activity in rats of Wistar strain.Several compounds in this series show hypolipidemic activity comparable with that of the standard drug clofibrate at 200 mg/kg (p.o) dose.