55705-15-2

Upstream product

• 532-32-1 sodium benzoate 
• 21086-33-9 2-bromo-1-(4-methoxyphenyl)-1-propanone 
• 27130-46-7 N-methyl-O-(phenylcarbonyl)hydroxylamine hydrochloride 
• 121-97-1 4-Methoxypropiophenone 
• 28330-55-4 N-(tert-butyloxycarbonyl)-N-methyl-O-benzoyl-hydroxylamine 
• 65-85-0 benzoic acid 
• 100-42-5 styrene 
• 108-88-3 toluene 
• 5349-60-0 1-(4-methoxyphenyl)-1-propanol 
• 100-52-7 benzaldehyde 
• 536-74-3 phenylacetylene 

Downstream Products

• 84672-19-5 4-(5-Methyl-2-phenyl-oxazol-4-yl)-phenol 
• 84686-94-2 2-{4-[2-(4-Chloro-phenyl)-5-methyl-oxazol-4-yl]-phenoxy}-butyric acid ethyl ester 
• 84671-81-8 2-{4-[2-(4-Chloro-phenyl)-5-methyl-oxazol-4-yl]-phenoxy}-propionic acid ethyl ester 
• 84671-98-7 2-{4-[2-(4-Chloro-phenyl)-5-methyl-oxazol-4-yl]-phenoxy}-butyric acid 
• 84671-79-4 2-Methyl-2-[4-(5-methyl-2-phenyl-oxazol-4-yl)-phenoxy]-propionic acid ethyl ester 
• 84671-78-3 2-[4-(5-Methyl-2-phenyl-oxazol-4-yl)-phenoxy]-propionic acid ethyl ester 
• 84671-77-2 [4-(5-Methyl-2-phenyl-oxazol-4-yl)-phenoxy]-acetic acid ethyl ester 
• 84671-96-5 2-Methyl-2-[4-(5-methyl-2-phenyl-oxazol-4-yl)-phenoxy]-propionic acid 
• 84672-13-9 4-(4-methoxyphenyl)-5-methyl-2-phenyloxazole 

Relevant academic research and scientific papers

Metal-free one-pot α-benzoxylation of benzylic alcohols with acids or aldehydes

A metal-free strategy has been developed for α-benzoxylation of benzylic alcohols with acids or aldehydes. The reaction proceeds via sequential oxidation and α-benzoxylation in one pot. Importantly, the reactions are performed in metal-free condition and utilize cheap aqueous TBHP as an oxidant, affording α-benzoxy ketones in moderate to good yields.

Copper-catalyzed α-C-H acyloxylation of carbonyl compounds with terminal alkynes

Herein, a copper/TBHP catalyst system for the α-C-H acyloxylation of carbonyl compounds is developed using terminal alkynes as the acyloxy source. A variety of carbonyl compounds and terminal alkynes are tolerated in this reaction. In addition, its possible mechanism is proposed.

I2/TBHP-mediated oxidative coupling of ketones and toluene derivatives: a facile method for the preparation of α-benzoyloxy ketones

An efficient oxidative approach was developed for the α-benzoyloxylation of ketones using tert-butyl hydroperoxide (TBHP). This process provided facile access to a wide range of α-benzoyloxy ketones in good to excellent yields via the direct oxidative α-benzoyloxylation of a structurally diverse series of ketones using simple arylmethane compounds.

Bu4NI-Catalyzed α-Oxyacylation of Carbonyl Compounds with Toluene Derivatives

A TBAI (tetrabutylammonium iodide)-catalyzed direct α-oxyacylation of carbonyl compounds from readily available toluene derivatives has been developed. The distinguished features of this metal-free protocol include the employment of simple starting material, a wide carbonyl compound scope, and mild reaction conditions.

NBu4NI-catalyzed α-benzoxylation of ketones with terminal aryl alkenes

A metal-free protocol for the α-benzoxylation of ketones has been developed by using terminal aryl alkenes as an arylcarboxy surrogate. Moderate to good yields were attained for a variety of propiophenones and acetophenones by using tetra-n-butylammonium iodide (TBAI) as the catalyst and tert-butyl hydroperoxide (TBHP) as the oxidant under ambient reaction conditions. An efficient synthesis for the α-benzoxylation of aryl ketones has been developed by using terminal aryl alkenes as the arylcarboxy surrogate. The products were obtained in moderate to good yields for a broad scope of substrates. Tetra-n-butylammonium iodide (TBAI) and tert-butyl hydroperoxide (TBHP) were employed as the catalyst and oxidant, respectively.

METHOD FOR PRODUCING ALPHA-ACYLOXYCARBONYL COMPOUND AND NOVEL ALPHA-ACYLOXYCARBONYL COMPOUND

A method for producing an α-acyloxycarbonyl compound of the present invention includes performing an intermolecular reaction between a carboxylic acid and a carbonyl compound selected from the group consisting of ketones, aldehydes, and esters, which have

A general method for the α-acyloxylation of carbonyl compounds

(Chemical Equation Presented) A simple, one-pot method for the α-acyloxylation of carbonyl compounds that proceeds at room temperature in the presence of both moisture and air has been developed. Treatment of a variety of aldehydes and both cyclic and acy

Potential Hypolipidemic Agents: Part I-Synthesis and Hypolipidemic Activity of Some 4-(2,5-Substituted oxazole-4-yl)phenoxyalkanoic Acid Derivatives

A series of 4-(2-aryl-5-alkyl-aryloxazol-4-yl)phenoxyalkanoic acid derivatives (VI, 1-32) have been synthesised by O-alkylation of the corresponding 2-aryl-4-(4-hydroxyphenyl)-5-alkyl/aryloxazoles (Va-g) and evaluated for their hypolipidemic activity in rats of Wistar strain.Several compounds in this series show hypolipidemic activity comparable with that of the standard drug clofibrate at 200 mg/kg (p.o) dose.