84677-87-2

Upstream product

• 100-52-7 benzaldehyde 
• 24848-20-2 4-amino-5-trifluoromethyl-4H-1,2,4-triazole-3-thiol 

Downstream Products

• 89071-25-0 VO(BFT)2*H₂O 
• 89061-29-0 HfO(BFT)2*H₂O 
• 89061-27-8 ZrO(BFT)2*H₂O 
• 89061-21-2 UO₂(BFT)2 
• 864871-19-2 C₂₆H₂₄F₆N₁₀S₂ 
• 1224727-11-0 C₁₉H₁₉F₃N₈S 
• 1224727-14-3 C₂₀H₂₁F₃N₈S 
• 1224727-20-1 C₂₁H₂₃F₃N₈S 
• 1335203-64-9 C₂₂H₂₃F₃N₆S 
• 1335203-70-7 C₂₂H₂₂ClF₃N₆S 
• 1335203-76-3 C₂₂H₂₁Cl₂F₃N₆S 

Relevant academic research and scientific papers

Synthesis of novel 1,2,4-triazoles and triazolo-thiadiazines as anticancer agents

A new series of 7-arylazo-5H-3-(tri uoromethyl)-6-methyl-1,2,4-triazolo-[3,4- b ]-1,3,4-thiadiazines was pre- pared by reaction of 4-amino-3-tri uoromethyl-5-mercapto-1,2,4-triazoles with N -aryl-2-oxo-propane hydrazonoyl chlo- ride in dioxane under re ux

Synthesis, structure and biological activity of novel 1,2,4-triazole Mannich bases containing a substituted benzylpiperazine moiety

A series of novel Mannich bases with trifluoromethyl-1,2,4-triazole and substituted benzylpiperazine moieties were synthesized. Their structures were confirmed by IR, 1H NMR and elemental analysis. The single crystal structure of compound 4r was also determined. The preliminary bioassays showed that most of the lead compounds had low herbicidal activity against Brassica campestris, Echinochloa crusgalli, and KARI enzyme. However, most of them exhibited significant fungicidal activity at the dosage of 50μg/mL toward five test fungi. Among the 18 novel compounds, several showed superiority over the commercial fungicide Triadimefon against Cercospora arachidicola and Fusarium oxysporum f. sp. cucumerinum during this study. Meanwhile, some compounds displayed plant growth regulatory activity at the dosage of 10μg/mL.

Synthesis and biological activity of some novel trifluoromethyl-substituted 1,2,4-triazole and bis(1,2,4-Triazole) mannich bases containing piperazine rings

A series of trifluoromethyl-substituted 1,2,4-triazole Mannich base 6 and bis(1,2,4-triazole) Mannich base 7 containing pyrimidinylpiperazine rings via the Mannich reaction were synthesized and characterized by infrared (IR), 1H nuclear magnetic resonance (NMR), and elemental analysis. The fungicidal tests indicated that most of compounds 6 and 7 possessed excellent fungicidal activity. Among 19 novel compounds, some showed superiority over commercial fungicides Dimethomorph, Thiophanate-methyl, Iprodione, and Zhongshengmycin. Some compounds also exhibited favorable herbicidal activity in the preliminary studies. On the basis of the comparative molecular field analysis (CoMFA), five novel compounds were subsequently synthesized, their activities were estimated fairly accurately, and compounds 6-A1 and 7-A2 displayed good fungicidal activity against Pseudoperonospora cubensis (96.9 and 84.9%) as 6h and 7c, respectively.