84713-52-0Relevant academic research and scientific papers
(o-Hydroxyphenyl)methylphosphonic acids: Synthesis and Potentiometric Determinations of their pKa Values
Boehmer, Volker,Vogt, Walter,Chafaa, Salah,Meullemeestre, Jean,Schwing, Marie-Jose,Vierling, Francois
, p. 139 - 149 (2007/10/02)
(o-Hydroxyphenyl)methylphosphonic acids are readily obtained from o-(bromomethyl)- or o-(hydroxymethyl)phenols and trialkyl phosphites.Subsequent hydrolysis leads to the corresponding phosphonic acids.For a series of such compounds, the pKa val
Aminolysis of Activated Esters Formed by Reaction of Carboxylate Salts with Strained Phosphonates and Phosphinates
Acher, Francine,Wakselman, Michel
, p. 3675 - 3676 (2007/10/02)
Nucleophilic attack of a carboxylate salt on a five membered phosphonic or phosphinic ester followed by an intramolecular acyl transfer reaction gives a substituted aryl ester.Due to the intramolecular base catalysis of a neighbouring P=O group the bimolecular aminolysis of this ester is a fast process.
