847145-84-0Relevant academic research and scientific papers
Pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis
Ghalit, Nourdin,Rijkers, Dirk T. S.,Kemmink, Johan,Versluis, Cees,Liskamp, Rob M. J.
, p. 192 - 194 (2005)
An alkene-bridged mimic of the complex DE-bisthioether-ring system of the antibiotic nisin was prepared in one step from the linear precursor.
Step-wise and pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis
Ghalit, Nourdin,Kemmink, Johan,Hilbers, Hans W.,Versluis, Cees,Rijkers, Dirk T. S.,Liskamp, Rob M. J.
, p. 924 - 934 (2007/10/03)
This paper describes two approaches for the synthesis of a crossed alkene-bridged mimic of the thioether ring system of the nisin Z DE-fragment. The first approach comprised the stepwise total synthesis featuring a cross metathesis and a macrolactamizatio
