84770-65-0Relevant academic research and scientific papers
Sulfated polyborate: mild, efficient and eco-friendly catalyst for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones
Khatri, Chetan K.,Patil, Manisha S.,Chaturbhuj, Ganesh U.
, p. 1683 - 1689 (2017/06/27)
Abstract: An efficient, inexpensive and recyclable sulfated polyborate catalyst was applied in a three-component, one-pot cyclocondensation of isatoic anhydride, aldehydes and ammonium acetate/amines to afford the corresponding 2,3-dihydroquinazolin-4(1H)-ones. The key advantages of the present method are high yields, short reaction time, easy workup, recyclability of catalyst and ability to tolerate a variety of functional groups which gives economical as well as ecological rewards. Graphical Abstract: [Figure not available: see fulltext.].
Hydroxyapatite nanoparticles (HAP NPs): A green and efficient heterogeneous catalyst for three-component one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media
Razavi, Nasrin,Akhlaghinia, Batool
, p. 447 - 457 (2016/01/12)
Hydroxyapatite nanoparticles (HAP NPs) are found to be an efficient catalyst for synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media via a three-component one-pot condensation of isatoic anhydride and aromatic aldehydes with primary amines or ammonium salts. The nanocatalyst (characterized by FT-IR, XRD, SEM-EDS and TEM techniques) is easily recyclable six times without the significant loss of catalytic activity. Other remarkable features include the wide range of functional group tolerance and good to excellent yields of the products under mild reaction conditions.
Nano-indium oxide: An efficient catalyst for one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones with a greener prospect
Santra, Sougata,Rahman, Matiur,Roy, Anupam,Majee, Adinath,Hajra, Alakananda
, p. 52 - 57 (2014/03/21)
Nano-In2O3 is found to be a remarkable efficient catalyst for the one-pot three-component condensation of isatoic anhydride, primary amine or ammonium salts and aromatic aldehydes for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in aqueous media. In2O3 nanoparticles are easily recyclable without the significant loss of catalytic activities.
Inclusion complex of Isatoic anhydride with β-cyclodextrin and supramolecular one-pot synthesis of 2, 3-dihydroquinazolin-4(1H)-ones in aqueous media
Patil, Dipak R.,Ingole, Pravin G.,Singh, Kripal,Dalal, Dipak S.
, p. 327 - 332 (2013/07/26)
The inclusion complex of isatoic anhydride with β-cyclodextrin was formed as a result of intermolecular interaction between isatoic anhydride with β-CD. The inclusion complex was confirmed by IR spectroscopy, X-ray diffraction and DSC studies. From application of complex, herein we have described a simple and efficient protocol for synthesis of 2, 3-dihydroquinazoline-4(1H)-one derivatives by one pot condensation of isatoic anhydride, ammonium acetate or amine and aldehyde using β-CD as a supramolecular catalyst in aqueous media.
Synthesis of 2,3-dihydroquinazolin-4(1H)-ones by three-component coupling of isatoic anhydride, amines, and aldehydes catalyzed by magnetic Fe 3O4 nanoparticles in water
Zhang, Zhan-Hui,Lue, Hong-Yan,Yang, Shu-Hong,Gao, Jian-Wu
experimental part, p. 643 - 646 (2010/10/20)
A simple and efficient protocol for one-pot three-component coupling of isatoic anhydride, amines, and aldehydes in water using magnetically recoverable Fe3O4 nanoparticles is reported. This methodology results in the synthesis of a variety of 2,3-dihydroquinazolin-4(1H)-ones in high yields. The catalyst can be recovered and recycled without a significant loss in the catalytic activity.
