84782-99-0Relevant academic research and scientific papers
The conjugate addition-aldol tandem reaction of α,β-unsaturated esters catalyzed by lithium benzenethiolate
Ono, Masashi,Nishimura, Katsumi,Nagaoka, Yasuo,Tomioka, Kiyoshi
, p. 1509 - 1512 (2007/10/03)
Reactions of α,β-unsaturated esters with aldehydes were catalyzed by 0.2 equiv of lithium benzenethiolate in the presence of phenyl trimethylsilyl sulfide to afford the conjugate addition-aldol tandem reaction products in the anti stereoselectivity and go
The Friedel-Crafts reaction of the Baylis-Hillman adducts
Basavaiah, Deevi,Krishnamacharyulu, Marimganti,Suguna Hyma, Rachakonda,Pandiaraju, Subramanian
, p. 2141 - 2144 (2007/10/03)
A simple and convenient methodology for the stereoselective construction of 2-benzyl substituted trisubstituted olefins via sulfuric acid catalyzed Friedel-Crafts reaction of benzene with Baylis-Hillman adducts is described.
Stereoselective α-Alkylation of α,β-Unsaturated Esters Utilizing Conjugate Addition of Nitrogen Nucleophiles (R2NLi)
Uyehara, Tadao,Asao, Naoki,Yamamoto, Yoshinori
, p. 1410 - 1411 (2007/10/02)
Treatment of α,β-unsaturated esters (1) with lithium amides i2 and LiN(CH2Ph)SiMe3> followed by alkylation and elimination of the amino groups produced trisubstituted enoates (2) with high stereoselectivity.
Methyl 4-Oxothiolane-3-carboxylate and Methyl 2-Methyl-4-oxothiolane-3-carboxylate Anions as Synthetic Equivalents of α-Acrylate and α-Crotonate Anions. Formal Synthesis of Integerrinecic Acid
Baraldi, Pier Giovanni,Guarneri, Mario,Pollini, Gian Piero,Simoni, Daniele,Barco, Achille,Benetti, Simonetta
, p. 2501 - 2505 (2007/10/02)
The base-promoted fragmentation of the C-alkylation products (6a-h) and (8a-e) of methyl 4-oxothiolane-3-carboxylate (4) and methyl 2-methyl-4-oxothiolane-3-carboxylate (5) gave good yields of the α-substituted acrylates (7a-h) and α-substituted crotonate
A Novel α-Acrylate Anion Equivalent: A Useful Synthon for α-Substituted Acrylic Esters
Baraldi, Pier Giovanni,Barco, Achille,Benetti, Simonetta,Moroder, Fabio,Pollini, Gian Piero,et al.
, p. 1265 - 1266 (2007/10/02)
An efficient preparation of α-substituted acrylic esters is described, based on the Dieckmann-Michael retrograde reactions of the C-alkylation products of 4-methoxycarbonylthiolan-3-one (1).
