847896-90-6Relevant articles and documents
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors
Groebke Zbinden, Katrin,Banner, David W.,Ackermann, Jean,D'Arcy, Allan,Kirchhofer, Daniel,Ji, Yu-Hua,Tschopp, Thomas B.,Wallbaum, Sabine,Weber, Lutz
, p. 817 - 822 (2007/10/03)
Proof of concept experiments have shown that tissue factor/factor VIIa inhibitors have antithrombotic activity without enhancing bleeding propensity. Starting from lead compounds generated by a biased combinatorial approach, phenylglycine amide tissue fac