848033-75-0

Basic information

• Product Name: (2S,4aS,7R,8aR)-(3-benzyl-4,4,7-trimethyloctahydro-2H-benzo[e][1,3]oxazin-2-yl)(4-methoxyphenyl)methanone
• Synonyms: (2S,4aS,7R,8aR)-(3-benzyl-4,4,7-trimethyloctahydro-2H-benzo[e][1,3]oxazin-2-yl)(4-methoxyphenyl)methanone
• CAS NO: 848033-75-0
• Molecular Weight: 407.553
• Mol File: 848033-75-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4aS,7R,8aR)-(3-benzyl-4,4,7-trimethyloctahydro-2H-benzo[e][1,3]oxazin-2-yl)(4-methoxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4aS,7R,8aR)-(3-benzyl-4,4,7-trimethyloctahydro-2H-benzo[e][1,3]oxazin-2-yl)(4-methoxyphenyl)methanone(848033-75-0)
• EPA Substance Registry System: (2S,4aS,7R,8aR)-(3-benzyl-4,4,7-trimethyloctahydro-2H-benzo[e][1,3]oxazin-2-yl)(4-methoxyphenyl)methanone(848033-75-0)

Safety Data

• Hazardous Substances Data: 848033-75-0(Hazardous Substances Data)

Upstream product

• 115156-56-4 (1R,2S,5R)-5-methyl-2-<1-methyl-1-(benzylamino)ethyl>cyclohexan-1-ol 
• 1076-95-5 p-methoxyphenylglyoxal 
• 16208-17-6 2,2-dihydroxy-1-(4-methoxyphenyl)ethan-1-one 

Downstream Products

• 848033-93-2 (1S,2S,2aS,3aR,5R,7aS)-2-(4-methoxyphenyl)-1-phenyl-5,8,8-trimethyl-octahydro-1H,3aH-azeto[2,1-b][1,3]benzoxazin-2-ol 
• 881748-14-7 (1S,2S',4a'S,7'R,8a'R)-1-(3-benzyl-4',4',7'-trimethyloctahydro-2H-benzo[e][1,3]oxazin-2'-yl)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethanol 
• 1026151-94-9 (2S,5R)-2-{1-[(2S,3R)-3-Benzyloxy-3-(4-methoxy-phenyl)-2-phenyl-azetidin-1-yl]-1-methyl-ethyl}-5-methyl-cyclohexanone 
• 848034-06-0 (2S,3R)-N-(8-mentholyl)-3-benzyloxy-3-(4-methoxyphenyl)-2-phenyl-azetidine 

Relevant articles and documents

An efficient synthesis of enantiomerically enriched trifluoromethylated 1,2-diols and 1,2-amino alcohols with quaternary stereocenters by diastereoselective addition of TMSCF3 to chiral 2-acyl-1,3- perhydrobenzoxazines

TMSCF3 adds to chiral 2-acyl-1,3-perhydrobenzoxazines with total diastereoselectivity leading to quaternary trifluoromethyl alcohols. Further transformation of the addition products yields enantiomerically enriched trifluoromethylated 1,2-diols