115156-56-4Relevant articles and documents
Asymmetric addition of chiral 1,3,2-benzoxazaphosphinine 2-oxides to aldehydes: Diastereoselective synthesis of α-substituted β-hydroxyphosphonic acids
Lopez, Beatriz,Maestro, Alicia,Pedrosa, Rafael
, p. 3012 - 3022 (2008/02/13)
The addition of stabilized phosphorus anions to aldehydes leads to α-substituted β-hydroxyphosphonates. The diastereoselectivity of the process is strongly influenced by the substitution of the phosphorus atom. Whereas P-ethyl derivatives provide a mixtur