84810-14-0

Basic information

• Product Name: 1,4-Epoxy-1H-2,3-benzodioxepin, 4,5-dihydro-5-methyl-1-phenyl-, (1R,4S,5R)-rel-
• CAS NO: 84810-14-0
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Mol File: 84810-14-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,4-Epoxy-1H-2,3-benzodioxepin, 4,5-dihydro-5-methyl-1-phenyl-, (1R,4S,5R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Epoxy-1H-2,3-benzodioxepin, 4,5-dihydro-5-methyl-1-phenyl-, (1R,4S,5R)-rel-(84810-14-0)
• EPA Substance Registry System: 1,4-Epoxy-1H-2,3-benzodioxepin, 4,5-dihydro-5-methyl-1-phenyl-, (1R,4S,5R)-rel-(84810-14-0)

Safety Data

• Hazardous Substances Data: 84810-14-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 22360-62-9 1-methyl-3-phenylindene 
• 77196-47-5 bis-(α-hydroxy-4-methylbenzyl) peroxide 
• 84847-60-9 endo-1-methyl-3-phenylindene ozonide 
• 64-19-7 acetic acid 
• 211867-05-9 (Z)-[2-(1-methyl-3-methoxy-2-propenyl)phenyl]phenylmethanone 
• 211867-15-1 Phenyl-{2-[1-(5-phenyl-5-trifluoromethyl-[1,2,4]trioxolan-3-yl)-ethyl]-phenyl}-methanone 
• 84810-25-3 2-(o-Benzoylphenyl)propanal 

Downstream Products

• 84847-64-3 endo-8-methyl-1-phenyl-4-tolyl9,10-benzo-2,3,5,6,11-pentaoxabicyclo<5.3.1>undecane 
• 84847-60-9 endo-1-methyl-3-phenylindene ozonide 
• 84810-40-2 exo-8-methyl-1-phenyl-4-tolyl9,10-benzo-2,3,5,6,11-pentaoxabicyclo<5.3.1>undecane 
• 50431-53-3 1-phenyl-4-methyl-1H-2-benzopyran 
• 93645-94-4 2-[2-(Hydroxy-phenyl-methyl)-phenyl]-propan-1-ol 
• 84810-47-9 cis-3,4-dihydro-1-phenyl-4-methyl-1H-2-benzopyran 
• 84810-46-8 trans-3,4-dihydro-1-phenyl-4-methyl-1H-2-benzopyran 
• 84810-25-3 2-(o-Benzoylphenyl)propanal 
• 73721-00-3 2-[2-(benzoyl)phenyl] propanoic acid 
• 84810-18-4 1-(2-benzoyloxyphenyl)propionaldehyde 
• 84810-22-0 2-(2-benzoyloxyphenyl)-2-methylethenol 
• 84810-41-3 (1S,8S,9R,12S)-1,8-Dimethyl-12-p-tolyl-10,11,13,14,15-pentaoxa-tricyclo[7.5.1.0^2,7]pentadeca-2⁽⁷⁾,3,5-triene 
• 84847-65-4 (1S,8R,9R,12S)-1,8-Dimethyl-12-p-tolyl-10,11,13,14,15-pentaoxa-tricyclo[7.5.1.0^2,7]pentadeca-2⁽⁷⁾,3,5-triene 
• 84810-29-7 methyl 1-(2-benzoylphenyl)propionate 

Relevant articles and documents

Ozonolyses of 1-Alkyl-Substituted 3-Methylindenes. Remarkable Effects of the Substituent Steric Bulk and the Stereochemistry of the Carbonyl Oxide Intermediates on the Efficiency of Ozonide Formation

Ozonolyses of 3-methyl- and 3-isopropyl-l-methylindenes (1a,b) in ether gave mainly the corresponding oligomers 3a,b, while in the case of 3-phenyl- and 3-tert-butyl-1-methylindenes (1c,d), the corresponding exo-endo mixtures of ozonides 2c,d were obtaine

Ozonolysis of 1-Methylindenes. Solvent, Temperature, and Substituent Electronic Effects on the Ozonide Exo/Endo Ratio

The ozonolyses of 1-methyl-3-aryl-, 1,2-dimethyl-3-aryl-, and 1-methyl-2,3-diarylindenes (1a-e, 4a-e, 7a-e, 7a',b',d') in various solvents at several temperatures have been undertaken.The data revealed the following. (a) The ozonolysis of indenes 1c, 4c,

Synthesis, X-ray Analysis, and Acidolysis of exo- and endo-1-Methylindene Ozonides

Ozonolyses of 2,3-disubstituted 1-methylindenes gave mixtures of the corresponding exo and endo ozonides.The structures of endo-1-methyl-3-phenylindene ozonide (3a) and exo-1-methyl-2,3-diphenylindene ozonide (2b) were determined by the X-ray analysis.Acidolysis of exo- and endo-1-methylindene ozonides 2a-d and 3a-d under several conditions revealed some characteristic features. (a) Antimony pentachloride or chlorosulfonic acid catalyzed the interconversion of the exo-endo ozonide isomers, the ratio in equilibrium being ca. 7:3 for all the pairs. (b) In the reaction of 3-methyl-substituted indene ozonides 2c,d and 3c,d in acetic-d3 acid-d a rapid hydrogen-deuterium exchange on the bridgehead methyl was observed. (c) In methylene chloride or acetic acid the ozonides decomposed very slowly, yielding the mixtures of rearranged products 4 and 5, carboxylic acid 6, and diketone 7; both the rate of decomposition and the product distribution being a marked function of the structure of the ozonides. (d) Methanol accelerated the decomposition of ozonides, the disappearance following pseudo-first-order kinetics.The rate decreased in the order 3a > 2a > 2b > 2c ca. 3c > 3b.This order was significantly different from the order observed in the reaction in acetic acid: 3b > 3c > 2b > 2c > 3a > 2a. (e) Reduction by AlHCl2 gave a mixture of 3,4-dihydro-1H-2-benzopyrans 19 - 22, the composition being significantly varied depending on the stereochemistry of the ozonides. (f) Treatment of 2a or 3a with bis(α-hydroxy-4-methylbenzyl)peroxide (31) gave two stereoisomeric peroxides 32a and 33a in roughly equal amounts.In contrast, the reaction of an exo ozonide 2d with a mixture of p-tolualdehyde and 30percent H2O2 (an equivalent of 31) afforded exclusively the corresponding exo peroxide 32d, while the endo isomer 3d gave predominantly the endo peroxide 33d.