84824-90-8

Usage

Chemical class

Urea derivative

Appearance

White, crystalline solid

Solubility

Sparingly soluble in water and organic solvents

Use in coordination chemistry

Ligand for metal ions

Biological properties

Exhibits anti-tumor and anti-bacterial properties

Synthesis application

Building block in the synthesis of various organic compounds

Potential applications

Medicinal chemistry and drug development

Unique structure

Versatile reactivity and diverse applications in chemical research and practical use

InChI:InChI=1/C13H14N4O/c18-13(16-9-11-1-5-14-6-2-11)17-10-12-3-7-15-8-4-12/h1-8H,9-10H2,(H2,16,17,18)

Upstream product

• 3731-53-1 4-(aminomethyl)pyridine 
• 64773-98-4 1-methyl-1-nitroso-3-(4-pyridylmethyl)urea 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 530-62-1 1,1'-carbonyldiimidazole 
• 57-13-6 urea 
• 87344-98-7 1-nitroso-1-phenyl-3-(4-pyridylmethyl)-urea 
• 102127-66-2 1-nitroso-3-(4-pyridylmethyl)-1-(4-tolyl)urea 

Relevant academic research and scientific papers

Synthesis, structural characterization and anion binding studies of palladium macrocycles with hydrogen-bonding ligands

The reactions between [Pd(P-P)(OTf)2] (where P-P = dppp or dppf) and two different bipyridyl ligands (L1 = 1,3-bis(4-pyridylmethyl) urea and L2 = 1,3- bis(pyridinylmethyl)benzenedicarboxamide) containing hydrogen-bonding units have been studied. The X-ray crystal structures of three of these assemblies have been solved showing them to be the [2 + 2] metallo-macrocycles [Pd(P-P)(Ln)]2(OTf) 4 [P-P = dppp, n = 1, (1); P-P = dppp, n = 2, (2); P-P = dppf, n = 1, (3)]. To confirm whether the dimeric assembly of one of these species (1) is retained in solution, several investigations have been carried out. 1H NMR studies in DMSO and high resolution ESI mass spectrometry have shown that 1 is in equilibrium with a larger [3 + 3] metallo-macrocycle. The equilibrium between these two species can be modified by changing the temperature, concentration or solvent. Also, addition of certain anions (e.g. [H2PO4]-) to the mixture shifts the equilibrium favoring the formation of the [2 + 2] metallo-macrocycle over the [3 + 3] (initially present in a larger proportion). The Royal Society of Chemistry.

PYRIDINIUM COMPOUNDS, A SYNTHESIS METHOD THEREFOR, METAL OR METAL ALLOY PLATING BATHS CONTAINING SAID PYRIDINIUM COMPOUNDS AND A METHOD FOR USE OF SAID METAL OR METAL ALLOY PLATING BATHS

The present invention concerns pyridinium compounds, a synthesis method for their preparation, metal or metal alloy plating baths containing said pyridinium compounds and a method for use of said metal or metal alloy plating baths. The plating baths are particularly suitable for use in filling of recessed structures in the electronics and semiconductor industry including dual damascene applications.

Equipping metallo-supramolecular macrocycles with functional groups: Assemblies of pyridine-substituted urea ligands

A series of di-(m-pyridyl)-urea ligands were prepared and characterized with respect to their conformations by NOESY experiments and crystallography. Methyl substitution in different positions of the pyridine rings provides control over the position of the pyridine N atoms relative to the urea carbonyl group. The ligands were used to self-assemble metallo-supramolecular M 2L2 and M3L3 macrocycles which are generated in a finely balanced equilibrium in DMSO and DMF according to DOSY NMR experiments and ESI FTICR mass spectrometry. Again, crystallography was used to characterize the assemblies. Methyl substitution in positions next to the pyridine nitrogen prevents coordination, while the other ligands form small metallo-supramolecular macrocycles. The incorporated urea carbonyl groups provide hydrogen bonding sites which converge towards the center of the assemblies. The Royal Society of Chemistry 2012.