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Usage

Uses

Used in Chemical Synthesis:
3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-one is used as a key intermediate in the synthesis of various organic compounds. Its unique structure with bromine and chlorine substituents allows for versatile chemical reactions, such as cross-coupling, substitution, and addition reactions, enabling the formation of a wide range of target molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-one is used as a building block for the development of novel drug candidates. Its structural features can be exploited to design and synthesize bioactive molecules with potential therapeutic applications, such as antimicrobial, antiviral, or anticancer agents.
Used in Material Science:
3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-one can be employed in the development of advanced materials, such as polymers, dyes, or sensors. Its bromine and chlorine substituents can impart specific properties to the resulting materials, such as enhanced stability, solubility, or optical characteristics, making them suitable for various applications in material science.
Used in Agrochemical Industry:
3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-one may also find applications in the agrochemical industry as a precursor for the synthesis of pesticides or herbicides. Its chemical properties can be tailored to create compounds with targeted biological activities, contributing to the development of more effective and environmentally friendly agrochemicals.

InChI:InChI=1/C16H14BrClO/c1-11(19)16(13-3-2-4-14(17)10-13)9-12-5-7-15(18)8-6-12/h2-8,10,16H,9H2,1H3

Upstream product

• 1204241-05-3 C₁₅H₁₁BrCl₂O 
• 676-58-4 methylmagnesium chloride 
• 150529-73-0 methyl 2-(3-bromophenyl)acetatee 
• 622-95-7 4-chlorobenzyl bromide 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 958851-00-8 4-(4-chlorophenyl)-3-(3-cyanophenyl)-2-methylsulfonyloxybutane 
• 958851-01-9 4-(4-chlorophenyl)-3-(3-cyanophenyl)-2-azidobutane 
• 732982-66-0 N-(1S,2S)-[2-(3-cyanophenyl)-3-(4-chlorophenyl)-1-methylpropyl]amine 
• 610791-48-5 N-(1S,2S)-[2-(3-cyanophenyl)-3-(4-chlorophenyl)-1-methylpropyl]amine hydrochloride 
• 958850-94-7 4-(4-chlorophenyl)-3-(3-bromophenyl)-2-butanol 
• 701977-00-6 N-[(1R,2R)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide 
• 701977-09-5 taranabant 
• 610791-48-5 N-[3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]amine hydrochloride 

Relevant academic research and scientific papers

SUBSTITUTED ESTERS AS CANNABINOID-1 RECEPTOR MODULATORS

Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present in

Discovery of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1- methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity

The discovery of novel acyclic amide cannabinoid-1 receptor inverse agonists is described. They are potent, selective, orally bioavailable, and active in rodent models of food intake and body weight reduction. A major focus of the optimization process was to increase in vivo efficacy and to reduce the potential for formation of reactive metabolites. These efforts led to the identification of compound 48 for development as a clinical candidate for the treatment of obesity.

RADIOLABELED CANNABINOID-1 RECEPTOR MODULATORS

The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.