848338-35-2Relevant academic research and scientific papers
Synthesis of 17β-estradiol-linked platinum(II) complexes and their cytocidal activity on estrogen-dependent and -independent breast tumor cells
Perron, Valerie,Rabouin, Daniel,Asselin, Eric,Parent, Sophie,C.-Gaudreault, Rene,Berube, Gervais
, p. 1 - 15 (2007/10/03)
The synthesis of two new highly potent 17β-estradiol-linked platinum(II) complexes is described. The new molecules are linked at position 16 of the steroid nucleus with an alkyl chain. They are made from estrone in nine chemical steps with an overall yiel
