848347-56-8

Upstream product

• 91-13-4 α,α'-dibromo-o-xylene 
• 25018-67-1 1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose 
• 848347-55-7 3-O-(2-bromomethyl)benzyl-1,2:4,5-di-O-isopropylidene-β-D-fructopyranose 

Downstream Products

• 59920-31-9 2,5-dideoxy-2,5-imino-D-mannitol 
• 132295-44-4 2,5-anhydro-2,5-imino-D-glucitol 

Relevant academic research and scientific papers

Intramolecular benzyl protection delivery: A practical synthesis of DMDP and DGDP from D-fructose

A two-step protection of 1,2-diols as the corresponding o-xylylene cyclic ethers, involving an intramolecular ring-closing O-benzylation reaction, has been developed to overcome the problems associated to regioselective benzylation reactions. The strategy has been applied to the high-yielding synthesis of the pyrrolidine glycosidase inhibitors DMDP and DGDP.