848470-22-4Relevant academic research and scientific papers
5-Lipoxygenase inhibition by N-hydroxycarbamates in dual-function compounds
Lewis, Timothy A.,Bayless, Lynn,DiPesa, Alan J.,Eckman, Joseph B.,Gillard, Michel,Libertine, Lyn,Scannell, Ralph T.,Wypij, Donna M.,Young, Michelle A.
, p. 1083 - 1085 (2005)
A series of N-hydroxycarbamates containing a histaminergic H1 receptor antagonist pharmacophore was synthesized. In vitro assays determined the compounds had both histaminergic binding and 5-lipoxygenase inhibiting activities comparable to the
