848474-34-0Relevant academic research and scientific papers
Rational Design of Programmable Monodisperse Semi-Synthetic Protein Nanomaterials Containing Engineered Disulfide Functionality**
Bhandari, Pavankumar Janardhan,Sandanaraj, Britto S.
, p. 2966 - 2972 (2021/08/07)
The reversible nature of disulfide functionality has been exploited to design intelligent materials such as nanocapsules, micelles, vesicles, inorganic nanoparticles, peptide and nucleic acid nanodevices. Herein, we report a new chemical methodology for t
Rapid Chemical Synthesis of Self-Assembling Semi-Synthetic Proteins
Bhandari, Pavankumar Janardhan,Rao, Kasuladevu Jegannadha,Reddy, Mullapudi Mohan,Sandanaraj, Britto S.
, p. 8576 - 8589 (2021/07/19)
The design of well-defined monodispersed self-assembling semi-synthetic proteins is emerging as a promising research avenue. These proteins hold great potential to be used as scaffolds for various protein nanotechnology applications. Currently, there are very few chemical methods reported; however, they suffer from elaborate multistep organic synthesis. Herein, we report a new chemical methodology for the rapid synthesis of a diverse set of semi-synthetic protein families, which include protein amphiphiles, facially amphiphilic protein-dendron conjugates, and pH-sensitive protein-dendron conjugates. This chemical method holds great potential to access a wide variety of semi-synthetic proteins in a short time.
GENERATION-DEPENDENT SUPRAMOLECULAR ASSEMBLIES OF PROTEIN-DENDRON CONJUGATES
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Page/Page column 22; 26-27, (2019/06/23)
The present invention discloses monodisperse protein-dendron conjugates that self-assemble to generation-dependent supramolecular protein assemblies of different size and surface charges. The invention further provides a process for synthesis of protein-dendron conjugates containing hydrophobic dendron of different generations.
Dendritic chiral phosphine lewis bases-catalyzed asymmetric aza-Morita-Baylis-Hillman reaction of N-sulfonated imines with activated olefins
Liu, Ying-Hao,Shi, Min
supporting information; experimental part, p. 122 - 128 (2009/04/10)
A series of polyether dendritic chiral phosphine Lewis bases was synthesized, and successfully applied to the asymmetric aza-Morita - Baylis - Hill -man reaction of N - sulfonated imines (N - arylmethyl -idene-4- methylbenzenesulfonamides) with methyl vin
Effect of guest molecule flexibility in access to dendritic interiors
Aathimanikandan, Sivakumar V.,Sandanaraj, Britto S.,Arges, Christopher G.,Bardeen, Christopher J.,Thayumanavan
, p. 2809 - 2812 (2007/10/03)
(Figure Presented) Dendrimers are attractive scaffolds for catalysis, since catalytic sites can be isolated and the catalysts are recoverable and reusable. Herein, we show that conformationally constrained molecules have better access to dendritic cores c
Probing every layer in dendrons
Sivanandan, Kulandaivelu,Aathimanikandan, Sivakumar V.,Arges, Christopher G.,Bardeen, Christopher J.,Thayumanavan
, p. 2020 - 2021 (2007/10/03)
Dendrons with a fluorescent probe in a specific location have been synthesized and characterized. Accessibility of guest molecules to each of these layers was then analyzed using an intermolecular photoinduced electron-transfer process. Comparisons of the
