848501-94-0

Basic information

• Product Name: 2-BROMO-THIAZOLE-4-CARBOXAMIDE
• Synonyms: 2-BROMO-THIAZOLE-4-CARBOXAMIDE;2-bromo-1,3-thiazole-4-carboxamide(SALTDATA: FREE);2-broMo-1,3-thiazole-4-carboxaMide;2-bromo-4-Thiazolecarboxamide
• CAS NO: 848501-94-0
• Molecular Formula: C4H3BrN2OS
• Molecular Weight: 207.05
• Mol File: 848501-94-0.mol

Chemical Properties

• Boiling Point: 390.7 °C at 760 mmHg
• Flash Point: 190.1 °C
• Appearance: /
• Density: 1.934 g/cm³
• Vapor Pressure: 2.61E-06mmHg at 25°C
• Refractive Index: 1.656
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 14.26±0.50(Predicted)
• CAS DataBase Reference: 2-BROMO-THIAZOLE-4-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-THIAZOLE-4-CARBOXAMIDE(848501-94-0)
• EPA Substance Registry System: 2-BROMO-THIAZOLE-4-CARBOXAMIDE(848501-94-0)

Safety Data

• Hazardous Substances Data: 848501-94-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-BROMO-THIAZOLE-4-CARBOXAMIDE is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its reactivity allows for the development of new drugs with potential therapeutic applications in treating a variety of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 2-BROMO-THIAZOLE-4-CARBOXAMIDE is utilized as a building block for the creation of novel agrochemicals. Its ability to react with different chemical entities enables the production of innovative compounds with potential applications in crop protection and pest control.
Used in Material Industry:
2-BROMO-THIAZOLE-4-CARBOXAMIDE is employed as a crucial component in the development of new materials. Its unique chemical properties contribute to the creation of advanced materials with specific characteristics, such as improved stability, reactivity, or other desirable traits for various applications in the material industry.
Used in Organic Synthesis:
As a versatile intermediate in organic chemistry, 2-BROMO-THIAZOLE-4-CARBOXAMIDE is used for the synthesis of a wide range of organic compounds. Its reactivity with nucleophiles and electrophiles makes it a valuable component in the production of various chemical entities for research and industrial purposes.

InChI:InChI=1/C4H3BrN2OS/c5-4-7-2(1-9-4)3(6)8/h1H,(H2,6,8)

Upstream product

• 5198-88-9 2-bromothiazole-4-carboxylic Acid 
• 1336-21-6 ammonium hydroxide 
• 100367-77-9 ethyl 2-bromothiazole-4-carboxylate 
• 170235-26-4 2-bromo-thiazole-4-carboxylic acid methyl ester 

Downstream Products

• 848501-90-6 2-bromothiazole-4-carbonitrile 

Relevant articles and documents

Corresponding amine nitrile and method of manufacturing thereof

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INHIBITORS OF BRUTON'S TYROSINE KINASE

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NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS

Novel compounds which are antagonists or inverse agonists at one or more of the opioid receptors, pharmaceutical compositions containing them, to processes for their preparation.

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A method of treatment using pharmaceutical compositions containing novel antagonists or inverse agonists at opioid receptors for the treatment of binge eating disorder, anorexia nervosa, bulimia nervosa, excess drug or alcohol use, or eating disorder not otherwise specified.

HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS

This invention provides cholesterol absorption inhibitors of Formula I: and the pharmaceutically acceptable salts thereof, wherein R12 is a hydroxylated alkyl group and R9 contains a heterocyclic ring. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating atherosclerosis and preventing atherosclerotic disease events.

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