848564-70-5Relevant academic research and scientific papers
Investigating chelating sulfonamides and their use in metalloproteinase inhibitors
Tanakit, Alisa,Rouffet, Matthieu,Martin, David P.,Cohen, Seth M.
experimental part, p. 6507 - 6515 (2012/09/21)
Matrix metalloproteinase inhibitors (MMPi) utilize zinc-binding groups (ZBGs) to chelate the catalytic Zn(ii) ion resulting in enzyme inhibition. Adapting findings from the literature of Zn(ii) ion sensors, we previously reported chelating sulfonamide inh
A simple and efficient one step synthesis of benzoxazoles and benzimidazoles from carboxylic acids
Wang, Ying,Sarris, Kathy,Sauer, Daryl R.,Djuric, Stevan W.
, p. 4823 - 4826 (2007/10/03)
Benzoxazoles or benzimidazoles can be rapidly and efficiently synthesized from a variety of carboxylic acids with 2-aminophenols or 1,2-phenylenediamines in one simple step, respectively. The use of commercially available PS-PPh3 resin combined with microwave heating delivered a variety of benzoxazoles and benzimidazoles in high yields and purities.
Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C
Lavergne, Olivier,Fernandes, Anne-Cecile,Brehu, Laetitia,Sidhu, Alban,Brezak, Marie-Christine,Prevost, Gregoire,Ducommun, Bernard,Contour-Galcera, Marie-Odile
, p. 171 - 175 (2007/10/03)
A focused set of heterocyclic quinones based on the benzothiazole, benzoxazole, benzimidazole, indazole and isoindole was prepared and screened with respect to the inhibition of the phosphatase activity of CDC25C. Benzoxazole- and benzothiazole-diones wer
Regioselective preparation of 5-amino- and 6-amino-1,3-benzoxazole-4,7- diones from symmetrical diaminophenol and aminoresorcinol
Bréhu, Laetitia,Fernandes, Anne-Cécile,Lavergne, Olivier
, p. 1437 - 1440 (2007/10/03)
Regioisomeric 5-amino- and 6-amino- 1,3-benzoxazole-4,7-diones were prepared from 2,6-diamino-4-methoxyphenol and 2-amino-5-methoxyresorcinol, respectively. These symmetrical precursors have the property to be antisymmetrical to each other with respect to
