848675-12-7Relevant academic research and scientific papers
Diverging DOS strategy using an allene-containing tryptophan scaffold and a library design that maximizes biologically relevant chemical space while minimizing the number of compounds
Painter, Thomas O.,Wang, Lirong,Majumder, Supriyo,Xie, Xiang-Qun,Brummond, Kay M.
, p. 166 - 174 (2011/06/18)
A diverging diversity-oriented synthesis (DOS) strategy using an allene-containing tryptophan as a key starting material was investigated. An allene-yne substituted derivative of tryptophan 12 gave indolylmethylazabicyclooctadiene 17 when subjected to a m
