848826-75-5Relevant academic research and scientific papers
Autoinductive exponential signal amplification: A diagnostic probe for direct detection of fluoride
Perry-Feigenbaum, Rotem,Sella, Eran,Shabat, Doron
experimental part, p. 12123 - 12128 (2011/11/28)
A new example of an exponential signal amplification strategy for the direct detection of fluoride is demonstrated. The amplification occurred through reaction of fluoride with a responsive chromogenic probe. The probe activity is based on a unique dendri
A cascade biodegradable polymer based on alternating cyclization and elimination reactions
DeWit, Matthew A.,Gillies, Elizabeth R.
supporting information; experimental part, p. 18327 - 18334 (2010/04/24)
Polymers that depolymerize by a cascade of intramolecular reactions in response to the removal of a stabilizing end-cap can allow for an unprecedented degree of control over the polymer degradation process. Described here is the development of polymers co
Single-triggered trimeric prodrugs
Haba, Keren,Popkov, Mikhail,Shamis, Marina,Lerner, Richard A.,Barbas, Carlos F.,Shabat, Doron
, p. 717 - 720 (2007/10/03)
The knock-on effect of a single catalytic reaction by a specific enzyme on a prodrug platform initiates the sequential collapse of the whole array to release the active drug units (see scheme). Such a dendritic system may provide a means to improve select
