848828-90-0

Upstream product

• 848828-80-8 (S)-1-benzyl-4-(1'-hydroxy-3'-methylpentan-2'-yl)-1,4-diazepan-5-one 
• 100-39-0 benzyl bromide 
• 7533-40-6 (S)-2-amino-4-methylpentan-1-ol 
• 61-90-5 L-leucine 
• 848828-70-6 (S)-2-azido-3-methylpentan-1-ol 

Relevant academic research and scientific papers

Modular synthesis of cyclic peptidomimetics inspired by γ-turns

(Chemical Equation Presented) A series of peptidomimetics based on a γ-turn motif were synthesized using a modular approach, in which N-protected piperidones were reacted with a selection of 2-hydroxyalkyl azides derived from common L-amino acids. Hydrolysis of the initially formed iminium ethers afforded the targeted series of substituted 1,4-diazepin-5-ones.