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2-BROMO-6-MORPHOLINOPYRAZINE is a pyrazine derivative chemical compound with the molecular formula C7H9BrN4O and a molecular weight of 227.077 g/mol. It features a bromine atom and a morpholine ring, and is characterized by its white to off-white crystalline solid appearance, which is soluble in organic solvents. Its properties render it suitable for a variety of chemical reactions and processes.

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  • 848841-62-3 Structure
  • Basic information

    1. Product Name: 2-BROMO-6-MORPHOLINOPYRAZINE
    2. Synonyms: 2-BROMO-6-MORPHOLINOPYRAZINE;4-(6-BROMOPYRAZIN-2-YL)MORPHOLINE
    3. CAS NO:848841-62-3
    4. Molecular Formula: C8H10BrN3O
    5. Molecular Weight: 244.1
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 848841-62-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 368.3 °C at 760 mmHg
    3. Flash Point: 176.5 °C
    4. Appearance: /
    5. Density: 1.57 g/cm3
    6. Vapor Pressure: 1.29E-05mmHg at 25°C
    7. Refractive Index: 1.583
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-BROMO-6-MORPHOLINOPYRAZINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-BROMO-6-MORPHOLINOPYRAZINE(848841-62-3)
    12. EPA Substance Registry System: 2-BROMO-6-MORPHOLINOPYRAZINE(848841-62-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 848841-62-3(Hazardous Substances Data)

848841-62-3 Usage

Uses

Used in Pharmaceutical Industry:
2-BROMO-6-MORPHOLINOPYRAZINE is used as a building block for the synthesis of various organic compounds, contributing to the development of new pharmaceuticals due to its versatile chemical structure.
Used in Agrochemical Production:
2-BROMO-6-MORPHOLINOPYRAZINE is utilized as an intermediate in the production of agrochemicals, playing a role in the creation of substances that help protect crops and enhance agricultural productivity.
Used in Dye Manufacturing:
In the dye industry, 2-BROMO-6-MORPHOLINOPYRAZINE is employed as an intermediate, contributing to the synthesis of dyes that are used in various applications, including textiles, plastics, and printing inks.
Used in Specialty Chemicals:
2-BROMO-6-MORPHOLINOPYRAZINE is also used in the production of specialty chemicals, where its unique properties are leveraged to create compounds for specific industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 848841-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,8,4 and 1 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 848841-62:
(8*8)+(7*4)+(6*8)+(5*8)+(4*4)+(3*1)+(2*6)+(1*2)=213
213 % 10 = 3
So 848841-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10BrN3O/c9-7-5-10-6-8(11-7)12-1-3-13-4-2-12/h5-6H,1-4H2

848841-62-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(6-Bromopyrazin-2-yl)morpholine

1.2 Other means of identification

Product number -
Other names 4-(6-Bromopyrazin-2-Yl)Morpholine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:848841-62-3 SDS

848841-62-3Downstream Products

848841-62-3Relevant articles and documents

Synthesis of Novel Pyrazine-Substituted 1 H -Pyrrole-2-carboxamides and Related Tethered Heterocycles

Borrows, Rachel,Fairley, Gary,Feron, Lyman J. L.,Grant, Emma,Greenwood, Ryan D. R.,Howells, Rachel L.,Hughes, Samantha,Lamont, Scott G.,Lenz, Eva,McGuire, Thomas M.,Simpson, Iain

, (2022/02/10)

As part of a drug discovery program, 4-pyrazin-2-yl-1H-pyrrole-2-carboxamides were accessed along with a number of bicyclic analogues. Routes to these compounds were largely absent from the scientific literature. The synthesis of a 4-(pyrazin-2-yl)-1H-pyrrole-2-carboxamide and several fused bicyclic analogues all using standard procedures (SNAr, borylation, C C cross couplings, hydrolysis, amide bond formation, cyclisation, halogenation, and alkylation) from readily available starting materials is reported. The synthetic sequences range from 4-2 steps per final compound, with yields of isolated intermediates ranging from 20 to ?100%.

1,4-DISUBSTITUTED ISOQUINILONE DERIVATIVES AS RAF-KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES

-

Page/Page column 66, (2010/02/11)

This invention relates to compounds of formula (I) wherein the variable substituents are described herein. The compounds are useful for the treatment of conditions and diseases characterized by an aberrant MAP kinase signaling pathway, such as cancer.

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