849059-79-6

Basic information

• Product Name: 2-Propenoic acid, 3-[4-[[3-(dimethylamino)-2,2-dimethylpropyl]amino]-3-nitrophenyl]-, (2E)-
• CAS NO: 849059-79-6
• Molecular Formula: C16H23N3O4
• Molecular Weight: 321.376
• Mol File: 849059-79-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-[4-[[3-(dimethylamino)-2,2-dimethylpropyl]amino]-3-nitrophenyl]-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-[4-[[3-(dimethylamino)-2,2-dimethylpropyl]amino]-3-nitrophenyl]-, (2E)-(849059-79-6)
• EPA Substance Registry System: 2-Propenoic acid, 3-[4-[[3-(dimethylamino)-2,2-dimethylpropyl]amino]-3-nitrophenyl]-, (2E)-(849059-79-6)

Safety Data

• Hazardous Substances Data: 849059-79-6(Hazardous Substances Data)

Upstream product

• 877065-30-0 3-(4-chloro-3-nitrophenyl)acrylic acid methyl ester 
• 53369-71-4 N,N,2,2-tetramethyl-1,3-propanediamine 
• 20797-48-2 (E)-4-chloro-3-nitrocinnamic acid 

Downstream Products

• 929018-77-9 (E)-3-[4-(3-dimethylamino-2,2-dimethylpropylamino)-3-nitrophenyl]acrylic acid methyl ester 

Relevant articles and documents

N-Hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides as novel histone deacetylase inhibitors: Design, synthesis, SAR studies, and in vivo antitumor activity

A series of N-hydroxy-1,2-disubstituted-1H-benzimidazol-5-yl acrylamides were designed and synthesized as novel HDAC inhibitors. General SAR has been established for the substituents at positions 1 and 2, as well as the importance of the ethylene group an

HETEROCYCLIC COMPOUNDS

The present invention relates to compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to heterocyclic compounds and methods for their preparation. These compounds may be useful as medicaments for the trea